Evidence map›Paper›PMID 30038612›Full record

ArticleFrontiers in immunology2018

Purinergic Cooperation Between P2Y

Maria Luiza Thorstenberg, Marcos Vinícius Rangel Ferreira, Natália Amorim, Claudio Canetti, Fernanda B Morrone, José Carlos Alves Filho, Robson Coutinho-Silva

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Purinergic Signaling in Ovarian Carcinoma.Advanced pharmaceutical bulletin · 2025
    Review
  4. Article
  5. Cysteinyl-leukotrienes promote cutaneous Leishmaniasis control.Frontiers in cellular and infection microbiology · 2023
    Article
  6. Article
  7. Physiologic roles of P2 receptors in leukocytes.Journal of leukocyte biology · 2022
    Review
  8. Review
  9. Review
  10. Review
  11. Clinical Significance of ROMs, OXY, SHp and HMGB-1 in Canine Leishmaniosis.Animals : an open access journal from MDPI · 2021
    Article
  12. Article
  13. P2RX7 at the Host-Pathogen Interface of Infectious Diseases.Microbiology and molecular biology reviews : MMBR · 2021
    Review
  14. Review
  15. P2YMediators of inflammation · 2020
    Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Maria Luiza ThorstenbergLaboratório de Imunofisiologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Marcos Vinícius Rangel FerreiraLaboratório de Imunofisiologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Natália AmorimLaboratório de inflamação, Instituto de Biofísica Carlos Chagas Filho, Rio de Janeiro, Brazil.
Claudio CanettiLaboratório de inflamação, Instituto de Biofísica Carlos Chagas Filho, Rio de Janeiro, Brazil.
Fernanda B MorroneLaboratório de Farmacologia Aplicada, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
José Carlos Alves FilhoDepartamento de Farmacologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
Robson Coutinho-SilvaLaboratório de Imunofisiologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Universidade Federal do Rio de Janeiro · BRInstituto de Biofísica Carlos Chagas FilhoPontifícia Universidade Católica do Rio Grande do Sul · BRUniversidade de Ribeirão Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The release of damage-associated molecular patterns, including uridine triphosphate (UTP) and adenosine triphosphate (ATP) to the extracellular milieu is a key component of innate immune response to infection. Previously, we showed that macrophage infection by the protozoan parasite

Indexed as

Leishmania amazonensisLTB4P2X7P2Y2PANX-1

Identifiers

PMID30038612
PMCPMC6046465
OpenAlexW2872677064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.