Evidence map›Paper›PMID 30038602›Full record

ArticleFrontiers in microbiology2018

Coordination of Growth, Chromosome Replication/Segregation, and Cell Division in

Nancy E Kleckner, Katerina Chatzi, Martin A White, Jay K Fisher, Mathieu Stouf

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Prokaryotic homeostasis - a solution to thrive and survive.Frontiers in molecular biosciences · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Using conditional independence tests to elucidate causal links in cell cycle regulation inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Plasmids Can Shift Bacterial Morphological Response against Antibiotic Stress.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Threshold accumulation of a constitutive protein explainsProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Review
  13. Article
  14. Molecular Characterization of theAntibiotics (Basel, Switzerland) · 2020
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nancy E KlecknerDepartment of Molecular and Cellular Biology Harvard University, Cambridge, MA, United States.
Katerina ChatziDepartment of Molecular and Cellular Biology Harvard University, Cambridge, MA, United States.
Martin A WhiteDepartment of Molecular and Cellular Biology Harvard University, Cambridge, MA, United States.
Jay K FisherRedbud Labs, Durham, NC, United States.
Mathieu StoufDepartment of Molecular and Cellular Biology Harvard University, Cambridge, MA, United States.
Harvard University · USRedbud Labs (United States) · US

Funding

ILLEGITIMATE RECOMBINATION BY DRUG RESISTANCE ELEMENTSR01GM025326 · NIGMS · HARVARD UNIVERSITY · PI KLECKNER, NANCY E · 1985 to 2019
$12.5M
NIGMS NIH HHS R01 GM025326
6 · The paper itself

Abstract

Bacterial cells growing in steady state maintain a 1:1:1 relationship between an appropriate mass increase, a round of DNA replication plus sister chromosome segregation, and cell division. This is accomplished without the cell cycle engine found in eukaryotic cells. We propose here a formal logic, and an accompanying mechanism, for how such coordination could be provided in

Indexed as

bacteriacell cycle coordinationcell divisionchromosomeDNA replicationE. colilicensing

Identifiers

PMID30038602
PMCPMC6046412
OpenAlexW2808452905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.