Evidence map›Paper›PMID 30038573›Full record

ReviewFrontiers in pharmacology2018

Potential Applications of Nanotechnology in Urological Cancer.

Ming-Hui He, Li Chen, Ting Zheng, Yu Tu, Qian He, Hua-Lin Fu, Ju-Chun Lin, Wei Zhang, Gang Shu, Lili He and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ming-Hui HeDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Li ChenDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ting ZhengDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yu TuDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Qian HeDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Hua-Lin FuDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ju-Chun LinDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Wei ZhangDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Gang ShuDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Lili HeCollege of Pharmacy, Southwest Minzu University, Chengdu, China.
Zhi-Xiang YuanDepartment of Pharmacy, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nowadays, the potential scope of nanotechnology in uro-oncology (cancers of the prostate, bladder, and kidney) is broad, ranging from drug delivery, prevention, and diagnosis to treatment. Novel drug delivery methods using magnetic nanoparticles, gold nanoparticles, and polymeric nanoparticles have been investigated in prostate cancer. Additionally, renal cancer treatment may be profoundly influenced by applications of nanotechnology principles. Various nanoparticle-based strategies for kidney cancer therapy have been proposed. Partly due to the dilution of drug concentrations by urine production, causing inadequate drug delivery to tumor cells in the treatment of bladder cancer, various multifunctional bladder-targeted nanoparticles have been developed to enhance therapeutic efficiency. In each of these cancer research fields, nanotechnology has shown several advantages over widely used traditional methods. Different types of nanoparticles improve the solubility of poorly soluble drugs, and multifunctional nanoparticles have good specificity toward prostate, renal, and bladder cancer. Moreover, nanotechnology can also combine with other novel technologies to further enhance effectivity. As our understanding of nanotechnologies grows, additional opportunities to improve the diagnosis and treatment of urological cancer are excepted to arise. In this review, we focus on nanotechnologies with potential applications in urological cancer therapy and highlight clinical areas that would benefit from nanoparticle therapy.

Indexed as

diagnosisnanoparticlesnanotechnologytherapyurological cancer

Identifiers

PMID30038573
PMCPMC6046453

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.