Evidence map›Paper›PMID 30038555›Full record

ArticleFood & nutrition research2018

Hypolipidemic activities of partially deacetylated α-chitin nanofibers/nanowhiskers in mice.

Wenbo Ye, Liang Liu, Juan Yu, Shilin Liu, Qiang Yong, Yimin Fan

Open access · goldAbstract read
In one paragraph

Article in Food & nutrition research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wenbo YeJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Key Lab of Biomass-Based Green Fuel and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing, China.
Liang LiuJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Key Lab of Biomass-Based Green Fuel and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing, China.
Juan YuJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Key Lab of Biomass-Based Green Fuel and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing, China.
Shilin LiuCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.
Qiang YongJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Key Lab of Biomass-Based Green Fuel and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing, China.
Yimin FanJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Key Lab of Biomass-Based Green Fuel and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing, China.
Nanjing Forestry University · CNHuazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Partially deacetylated α-chitin nanofibers/nanowhiskers mixtures (DEChNs) were prepared by 35% sodium hydroxide (NaOH) treatment followed by disintegration in water at pH 3-4. The aim of this study was to investigate the hypolipidemic effects of DEChNs at different dosage levels in male Kunming mice. The male mice were randomly separated into five groups, that is, a normal diet group, a high-fat diet group, and three DEChN groups that were treated with different doses of DEChN dispersions (L: low dose, M: medium dose, H: high dose). Primarily, the DEChNs significantly decreased body weight (BW) gain and adipose tissue weight (ATW) gain of mice. Meanwhile, the decreasing extent of weight ratios between ATW and BW was dependent on the dose of DEChNs. Moreover, the DEChNs prevented an increase in plasma lipids (cholesterol and triacylglycerol) in mice when they were fed a high-fat diet. Histopathological examination of hepatocytes revealed that the DEChNs were effective in decreasing the accumulation of lipids in the liver and preventing the development of a fatty liver. The results suggested that the DEChNs reduced the absorption of dietary fat and cholesterol

Indexed as

chitincholesterolhypolipidemic effectsnanofibers/nanowhiskers

Identifiers

PMID30038555
PMCPMC6052507
OpenAlexW2883476631

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.