Evidence map›Paper›PMID 30038514›Full record

ArticleInternational journal of nephrology and renovascular disease2018

Atherosclerotic vascular disease and its correlates in stable black South African kidney transplant recipients.

Stephen Olawale Oguntola, Muzamil Olamide Hassan, Raquel Duarte, Therese Dix-Peek, Caroline Dickens, Gbenga Olorunfemi, Ahmed Vachiat, Graham Paget, Pravin Manga, Saraladevi Naicker

Open access · goldAbstract read
In one paragraph

Article in International journal of nephrology and renovascular disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Stephen Olawale OguntolaDepartment of Internal Medicine, Division of Nephrology, University of Witwatersrand, Johannesburg, South Africa, Olawaleogun1@gmail.com.
Muzamil Olamide HassanDepartment of Internal Medicine, Dialysis Unit, Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Nigeria.
Raquel Duarte *Department of Internal Medicine Laboratory, University of Witwatersrand, Johannesburg, South Africa.
Therese Dix-PeekDepartment of Internal Medicine Laboratory, University of Witwatersrand, Johannesburg, South Africa.
Caroline DickensDepartment of Internal Medicine Laboratory, University of Witwatersrand, Johannesburg, South Africa.
Gbenga OlorunfemiDepartment of Epidemiology and Biostatistics, School of Public Health, University of Witwatersrand, Johannesburg, South Africa.
Ahmed VachiatDepartment of Internal Medicine, Division of Cardiology, University of Witwatersrand, Johannesburg, South Africa.
Graham PagetDepartment of Internal Medicine, Division of Nephrology, University of Witwatersrand, Johannesburg, South Africa, Olawaleogun1@gmail.com.
Pravin MangaDepartment of Internal Medicine, Division of Cardiology, University of Witwatersrand, Johannesburg, South Africa.
Saraladevi Naicker *Department of Internal Medicine, Division of Nephrology, University of Witwatersrand, Johannesburg, South Africa, Olawaleogun1@gmail.com.
University of the Witwatersrand · ZALadoke Akintola University of Technology Teaching Hospital · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite remarkable improvement in renal function attributable to kidney transplantation, the burden of cardiovascular disease (CVD) among kidney transplant recipients (KTRs) remains high in the post-transplant period. Aggressive use of statins in KTRs may make lipoprotein ratios correlate better with atherosclerotic vascular disease (AsVD) when compared with traditional lipid profile parameters. We therefore evaluated the clinical and echocardiographic correlates of AsVD among non-diabetic, stable, black KTRs in South Africa.

methodsThis was a cross-sectional study of 41 adult (18-65 years), non-diabetic, stable KTRs and 41 age- and sex-matched healthy controls. An interviewer-administered questionnaire was used to obtain information on participants' sociodemographic and cardiovascular risk factors. Anthropometric parameters were measured. Urine and blood samples were obtained and analyzed. Echocardiography was performed and carotid intima media thickness (CIMT) was assessed in both right and left carotid arteries. Spearman's rank correlation and binary logistic regression were performed to determine the relationship between CVD risk factors and AsVD.

resultsAsVD was present in 46.3% of KTRs compared to 17.1% of healthy controls (

conclusionAsVD was common among KTRs. Older age and kidney transplant status independently predicted AsVD. Castelli index 2 and LCI correlated with AsVD better than serum lipid parameters.

Indexed as

carotid intima media thicknessCastelli index 2left ventricular mass indexlipoprotein combine indexlipoprotein ratios

Identifiers

PMID30038514
PMCPMC6053296
OpenAlexW2883826566

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.