ReviewWorld journal of gastroenterology2018
Perioperative thromboprophylaxis in liver transplant patients.
Review in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Comparing the efficacy and safety of thromboprophylaxis with enoxaparin versus normal saline after liver transplantation: randomized clinical trial.The British journal of surgery · 2025Trial
- Beyond Rebalanced Haemostasis: Haemostatic Phenotypes, Thrombin Generation, and Clinical Risk in Chronic Liver Disease.TH open : companion journal to thrombosis and haemostasis · 2026Review
- Development and internal validation of a nomogram for early prediction of deep vein thrombosis after liver transplantation: an exploratory machine-learning comparison.Frontiers in medicine · 2026Article
- Portal Vein Thrombosis, Management and Approaches in Liver Transplantation: A Narrative Review.Journal of clinical medicine · 2025Review
- Hepatic Artery Thrombosis After Orthotopic Liver Transplant: A 20-Year Monocentric Series.Journal of clinical medicine · 2025Article
- Thrombotic complications post liver transplantation: Etiology and management.World journal of critical care medicine · 2024Review
- Viscoelastic Hemostatic Testing as a Diagnostic Tool for Hypercoagulability in Liver Transplantation: A Narrative Review.Journal of clinical medicine · 2024Review
- Antiplatelet Prophylaxis Reduces the Risk of Early Hepatic Artery Thrombosis Following Liver Transplantation in High-Risk Patients.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Early pandemic in-hospital outcomes and mortality risk factors in COVID-19 solid organ transplant patients.Proceedings (Baylor University. Medical Center) · 2024Article
- Increased Platelet Aggregation in Adults After Orthotopic Liver Transplantation Indicates Higher Probability of Early Postoperative Survival.Annals of transplantation · 2023Article
- Educational Review: Error traps in anesthesia for pediatric liver transplantation.Paediatric anaesthesia · 2022Review
- 2020 Clinical Update in Liver Transplantation.Journal of cardiothoracic and vascular anesthesia · 2022Review
- Effects of total laparoscopic hysterectomy on the clinical outcomes of patients with uterine fibroids.American journal of translational research · 2022Article
- Vascular surgery in liver resection.Langenbeck's archives of surgery · 2021Review
- Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation.World journal of gastroenterology · 2021Article
- Impact of Hepatic Artery Variations and Reconstructions on the Outcome of Orthotopic Liver Transplantation.World journal of surgery · 2020Article
- Hepatic Artery Thrombosis and Takotsubo Syndrome After Liver Transplantation - Which Came First?The American journal of case reports · 2020Article
- Perioperative thrombelastography serves as an important assessment tool of transfusion requirements during liver transplantation.Surgery open science · 2020Article
- Projected 20- and 30-Year Outcomes for Pediatric Liver Transplant Recipients in the United States.Journal of pediatric gastroenterology and nutrition · 2020Article
- Liver function after transplantation in the assessment of the coagulation system and the concept of antithrombotic therapy.Przeglad gastroenterologiczny · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Improvements in surgical and anesthetic procedures have increased patient survival after liver transplantation (LT). However, the perioperative period of LT can still be affected by several complications. Among these, thromboembolic complications (intracardiac thrombosis, pulmonary embolism, hepatic artery and portal vein thrombosis) are relatively common causes of increased morbidity and mortality. The benefit of thromboprophylaxis in general surgical patients has already been established, but it is not the standard of care in LT recipients. LT is associated with a high bleeding risk, as it is performed in a setting of already unstable hemostasis. For this reason, the role of routine perioperative prophylactic anticoagulation is usually restricted. However, recent data have shown that the bleeding tendency of cirrhotic patients is not an expression of an acquired bleeding disorder but rather of coexisting factors (portal hypertension, hypervolemia and infections). Furthermore, in cirrhotic patients, the new paradigm of ''rebalanced hemostasis'' can easily tip towards hypercoagulability because of the recently described enhanced thrombin generation, procoagulant changes in fibrin structure and platelet hyperreactivity. This new coagulation balance, along with improvements in surgical techniques and critical support, has led to a dramatic reduction in transfusion requirements, and the intraoperative thromboembolic-favoring factors (venous stasis, vessels clamping, surgical injury) have increased the awareness of thrombotic complications and led clinicians to reconsider the limited use of anticoagulants or antiplatelets in the postoperative period of LT.
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