Evidence map›Paper›PMID 30038461›Full record

ArticleWorld journal of gastroenterology2018

Indocyanine green-based fluorescence imaging in visceral and hepatobiliary and pancreatic surgery: State of the art and future directions.

Gian Luca Baiocchi, Michele Diana, Luigi Boni

3 registry-linked trialsOpen access · hybridAbstract readEditorial
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04107623 nacompletednot on this mapstarted 2020, after this paper: background citation

Quantitative Fluorescent Guided Robotic Surgery for Cancer of the Gastroesophageal Junction

TypeinterventionalSponsorRigshospitalet, DenmarkRan2020 to 2021Enrolled70ConditionsStomach Neoplasms, SurgeryArmsIndocyanine Green
NCT05354856 phase4terminatednot on this mapstarted 2022, after this paper: background citation

The Effect of Chemoradiotherapy on Gastric Perfusion in Patients With Gastric Cancer.

TypeinterventionalSponsorRigshospitalet, DenmarkRan2022 to 2023Enrolled11ConditionsGastric CancerArmsIndocyanine green
NCT06198400 narecruitingnot on this mapstarted 2024, after this paper: background citation

Indocyanine Green Fluorescence in Evaluation of Post-resection Pancreatic Remnant Perfusion After Pancreaticoduodenectomy

TypeinterventionalSponsorCharles University, Czech RepublicRan2024 to 2027Enrolled60ConditionsPancreatic FistulaArmsPerioperative assessment of the perfusion of post-resection pancreatic remnant using indocyanine green-VerDye
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

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  18. Indocyanine green: The guide to safer and more effective surgery.World journal of gastrointestinal surgery · 2024
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gian Luca BaiocchiDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia 25125, Italy. gianluca.baiocchi@unibs.it.
Michele DianaIHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg 67000, France.
Luigi BoniGeneral and Emergency Surgery, IRCCS - Ca' Granda - Policlinico Hospital, Milan 20122, Italy.
Institut de Chirurgie Guidée par l'Image · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the use of fluorescence-guided surgery (FGS) to treat benign and malignant visceral, hepatobiliary and pancreatic neoplasms has significantly increased. FGS relies on the fluorescence signal emitted by injected substances (fluorophores) after being illuminated by ad hoc laser sources to help guide the surgical procedure and provide the surgeon with real-time visualization of the fluorescent structures of interest that would be otherwise invisible. This review surveys and discusses the most common and emerging clinical applications of indocyanine green (ICG)-based fluorescence in visceral, hepatobiliary and pancreatic surgery. The analysis, findings, and discussion presented here rely on the authors' significant experience with this technique in their medical institutions, an up-to-date review of the most relevant articles published on this topic between 2014 and 2018, and lengthy discussions with key opinion leaders in the field during recent conferences and congresses. For each application, the benefits and limitations of this technique, as well as applicable future directions, are described. The imaging of fluorescence emitted by ICG is a simple, fast, relatively inexpensive, and harmless tool with numerous different applications in surgery for both neoplasms and benign pathologies of the visceral and hepatobiliary systems. The ever-increasing availability of visual systems that can utilize this tool will transform some of these applications into the standard of care in the near future. Further studies are needed to evaluate the strengths and weaknesses of each application of ICG-based fluorescence imaging in abdominal surgery.

Indexed as

Digestive System Surgical ProceduresFluorescent DyesHumansIndocyanine GreenOptical ImagingSurgery, Computer-AssistedFluorescent DyesIndocyanine GreenBiliary anatomyBiliary surgeryFluorescence imagingGastrointestinal surgeryIndocyanine greenLiver surgeryPancreatic surgeryPeritoneal carcinomatosisVisceral perfusion

Identifiers

PMID30038461
PMCPMC6054946
OpenAlexW2884677567

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.