ArticleScientific reports2018
The Effect of SkitoSnack, an Artificial Blood Meal Replacement, on Aedes aegypti Life History Traits and Gut Microbiota.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- SkitoSnack 2.0 - A Bloodmeal Alternative for Anopheles and Aedes Mosquitoes.PLoS neglected tropical diseases · 2026Article
- Small mosquitoes: large implications-effects of larval crowding and starvation on locomotor activity, adult biting frequency, and insecticide resistance in two strains of Aedes aegypti.Parasites & vectors · 2025Article
- The artificial meal SkitoSnack does not support reproduction in Culex pipiens (Diptera: Culicidae) mosquitoes.Journal of insect science (Online) · 2025Article
- Characteristics of a Spray-Dried Porcine Blood Meal forInsects · 2024Article
- Purified fibers in chemically defined synthetic diets destabilize the gut microbiome of an omnivorous insect model.bioRxiv : the preprint server for biology · 2024Article
- The dynamics of the midgut microbiome inPNAS nexus · 2024Article
- Effects of a blood-free mosquito diet on fitness and gonotrophic cycle parameters of laboratory reared Anopheles gambiae sensu stricto.Parasites & vectors · 2024Article
- Infectivity of Plasmodium parasites to Aedes aegypti and Anopheles stephensi mosquitoes maintained on blood-free meals of SkitoSnack.Parasites & vectors · 2024Article
- The midgut epithelium of mosquitoes adjusts cell proliferation and endoreplication to respond to physiological challenges.BMC biology · 2024Article
- A critical review of current laboratory methods used to evaluate mosquito repellents.Frontiers in insect science · 2024Review
- Purified fibers in chemically defined synthetic diets destabilize the gut microbiome of an omnivorous insect model.Frontiers in microbiomes · 2024Article
- Effects of blood meal source on blood consumption and reproductive success of cat fleas, Ctenocephalides felis.PLoS neglected tropical diseases · 2023Article
- Batch RearingCold Spring Harbor protocols · 2023Article
- TargetingViruses · 2023Review
- A transcriptomic atlas ofeLife · 2022Article
- Ad libitum consumption of protein- or peptide-sucrose solutions stimulates egg formation by prolonging the vitellogenic phase of oogenesis in anautogenous mosquitoes.Parasites & vectors · 2022Article
- ATP-sensitive inward rectifier potassium channels reveal functional linkage between salivary gland function and blood feeding in the mosquito, Aedes aegypti.Communications biology · 2022Article
- Article
- Glucose metabolomic profile during embryogenesis in the tick Rhipicephalus microplus.Metabolomics : Official journal of the Metabolomic Society · 2021Article
- Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Public health research and vector control frequently require the rearing of large numbers of vector mosquitoes. All target vector mosquito species are anautogenous, meaning that females require vertebrate blood for egg production. Vertebrate blood, however, is costly, with a short shelf life. To overcome these constraints, we have developed SkitoSnack, an artificial blood meal replacement for the mosquito Aedes aegypti, the vector of dengue, Zika and chikungunya virus. SkitoSnack contains bovine serum albumin and hemoglobin as protein source as well as egg yolk and a bicarbonate buffer. SkitoSnack-raised females had comparable life history traits as blood-raised females. Mosquitoes reared from SkitoSnack-fed females had similar levels of infection and dissemination when orally challenged with dengue virus type 2 (DENV-2) and significantly lower infection with DENV-4. When SkitoSnack was used as a vehicle for DENV-2 delivery, blood-raised and SkitoSnack-raised females were equally susceptible. The midgut microbiota differed significantly between mosquitoes fed on SkitoSnack and mosquitoes fed on blood. By rearing 20 generations of Aedes exclusively on SkitoSnack, we have proven that this artificial diet can replace blood in mosquito mass rearing.
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