Evidence map›Paper›PMID 30038333›Full record

ArticleNature communications2018

Non-integumentary melanosomes can bias reconstructions of the colours of fossil vertebrates.

Maria E McNamara, Jonathan S Kaye, Michael J Benton, Patrick J Orr, Valentina Rossi, Shosuke Ito, Kazumasa Wakamatsu

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. From melanogenesis to melanin technologies.Communications chemistry · 2025
    Review
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Recent advances in amniote palaeocolour reconstruction and a framework for future research.Biological reviews of the Cambridge Philosophical Society · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Tissue-specific geometry and chemistry of modern and fossilized melanosomes reveal internal anatomy of extinct vertebrates.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Maria E McNamaraSchool of Biological, Earth and Environmental Sciences, University College Cork, North Mall, Cork, T23 TK30, Ireland. maria.mcnamara@ucc.ie.ORCID http://orcid.org/0000-0003-0968-4624
Jonathan S KayeSchool of Earth Sciences, University of Bristol, Queen's Road, Bristol, BS8 1RJ, UK.
Michael J BentonSchool of Earth Sciences, University of Bristol, Queen's Road, Bristol, BS8 1RJ, UK.ORCID http://orcid.org/0000-0002-4323-1824
Patrick J OrrUCD School of Earth Sciences, University College Dublin, Belfield, Dublin, D04D1W8, Ireland.
Valentina RossiSchool of Biological, Earth and Environmental Sciences, University College Cork, North Mall, Cork, T23 TK30, Ireland.
Shosuke ItoDepartment of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, 470-1192, Japan.
Kazumasa WakamatsuDepartment of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, 470-1192, Japan.ORCID http://orcid.org/0000-0003-1748-9001
Fujita Health University · JPUniversity College Cork · IEUniversity of Bristol · GBUniversity College Dublin · IE

Funding

EC | European Research Council (ERC) 2014-ERC-STG-637691
6 · The paper itself

Abstract

The soft tissues of many fossil vertebrates preserve evidence of melanosomes-micron-scale organelles that inform on integumentary coloration and communication strategies. In extant vertebrates, however, melanosomes also occur in internal tissues. Hence, fossil melanosomes may not derive solely from the integument and its appendages. Here, by analyzing extant and fossil frogs, we show that non-integumentary melanosomes have high fossilization potential, vastly outnumber those from the skin, and potentially dominate the melanosome films preserved in some fossil vertebrates. Our decay experiments show that non-integumentary melanosomes usually remain in situ provided that carcasses are undisturbed. Micron-scale study of fossils, however, demonstrates that non-integumentary melanosomes can redistribute through parts of the body if carcasses are disturbed by currents. Collectively, these data indicate that fossil melanosomes do not always relate to integumentary coloration. Integumentary and non-integumentary melanosomes can be discriminated using melanosome geometry and distribution. This is essential to accurate reconstructions of the integumentary colours of fossil vertebrates.

Indexed as

ColorFossilsAnimalsAnuraBiological EvolutionFeathersIguanasMelaninsMelanosomesPigmentationSkinVertebratesXenopusXenopus laevisMelanins

Identifiers

PMID30038333
PMCPMC6056411
OpenAlexW2824613164

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.