Evidence map›Paper›PMID 30038143›Full record

ReviewIndian journal of ophthalmology2018

Intravitreal therapeutic agents in noninfectious uveitic macular edema.

Kunal Kaushik Shah, Parthopratim Dutta Majumder, Jyotirmay Biswas

Open access · diamondAbstract readReview
In one paragraph

Review in Indian journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Intravitreal Methotrexate.Journal of ophthalmic & vision research
    Review
  2. Treatment of non-infectious retinal vasculitis.Therapeutic advances in ophthalmology
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kunal Kaushik ShahShri Bhagwan Mahavir VitreoRetinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Parthopratim Dutta MajumderDepartment of Uvea, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Jyotirmay BiswasDepartment of Uvea, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Sankara Nethralaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of uveitis is challenging for most treating ophthalmologists. The treatment of uveitis often requires the use of high dose of systemic corticosteroid and immunosuppressive agents, which are almost always associated with potential side effects. Intravitreal medications have become a popular mode of drug administration in uveitis patients as they provide high volume of drug to the target tissues, eliminating the risk of systemic toxicity. There has been tremendous development in the intravitreal therapeutics over the last few years. With the advent of sustained-release technique, increasing patient compliance, biodegradable nature of the implant, and introduction of newer agents with better safety profile, the intravitreal medications have become more popular in recent years. This review presents evidence in the scientific literature supporting the use of intravitreal medications for the management of uveitis and its complications.

Indexed as

Macular EdemaUveitisDrug ImplantsGlucocorticoidsHumansImmunosuppressive AgentsIntravitreal InjectionsDrug ImplantsGlucocorticoidsImmunosuppressive AgentsAnti-vascular endothelial growth factor agentsdexamethasonefluocinolone acetonideintravitreal agentsmethotrexatenoninfectious uveitissirolimustriamcinolone acetonide

Identifiers

PMID30038143
PMCPMC6080427
OpenAlexW2884825490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.