Evidence map›Paper›PMID 30038048›Full record

ArticleJournal of bacteriology2018

Inhibition of the Protein Phosphatase CppA Alters Development of Chlamydia trachomatis.

Ja E Claywell, Lea M Matschke, Kyle N Plunkett, Derek J Fisher

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. The Small Molecule H89 InhibitsInfection and immunity · 2021
    Article
  4. Protein Serine/Threonine Phosphatase Type 2C ofFrontiers in cellular and infection microbiology · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ja E ClaywellDepartment of Microbiology, Southern Illinois University, Carbondale, Illinois, USA.
Lea M MatschkeDepartment of Microbiology, Southern Illinois University, Carbondale, Illinois, USA.
Kyle N PlunkettDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, Illinois, USA.ORCID 0000-0002-5691-7876
Derek J FisherDepartment of Microbiology, Southern Illinois University, Carbondale, Illinois, USA fisher@micro.siu.edu.ORCID 0000-0002-1663-8389
Southern Illinois University Carbondale · US

Funding

Unraveling the role of protein phosphorylation in the regulation of development in Chlamydia trachomatisR15AI109566 · NIAID · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI FISHER, DEREK JAMES · 2014 to 2020
$887k
NIAID NIH HHS R15 AI109566
6 · The paper itself

Abstract

Chlamydiae are obligate intracellular Gram-negative bacterial pathogens that undergo an essential, but poorly understood, biphasic developmental cycle transitioning between the infectious elementary body and the replicative reticulate body. Ser/Thr/Tyr phosphorylation has been increasingly recognized for its role in regulating bacterial physiology.

Indexed as

AnimalsBacterial ProteinsCell LineChlamydia trachomatisGene Expression Regulation, BacterialHeLa CellsHumansMicePhosphorylationProtein Phosphatase 2CSalicylates5,5'-methylenedisalicylic acidBacterial ProteinsProtein Phosphatase 2CSalicylatesbacterial developmentChlamydia trachomatisphysiological effects of drugsprotein phosphataseprotein phosphorylation

Identifiers

PMID30038048
PMCPMC6148467
OpenAlexW2883596262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.