Evidence map›Paper›PMID 30038030›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner.

Zijie Su, Jiaxing Song, Zhongyuan Wang, Liang Zhou, Yuqing Xia, Shubin Yu, Qi Sun, Shan-Shan Liu, Liang Zhao, Shiyue Li and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Inhibition of Casein Kinase 1International journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Zijie SuGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Jiaxing SongGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Zhongyuan WangGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Liang ZhouGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Yuqing XiaGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Shubin YuGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Qi SunGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Shan-Shan LiuGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Liang ZhaoGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Shiyue LiGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China.
Lei WeiDepartment of Pathology and Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071 Hubei, China.
Dennis A CarsonGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China; dcarson@ucsd.edu delu@szu.edu.cn.
Desheng LuGuangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, 518060 Guangdong, China; dcarson@ucsd.edu delu@szu.edu.cn.
Shenzhen University Health Science Center · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tumor promoter 12-

Indexed as

AnimalsAxin Proteinbeta CateninCarcinogenesisCarcinogensCasein Kinase 1 epsilonCasein Kinase IdeltaCell Line, TumorDisease Models, AnimalFibroblastsHEK293 CellsHumansLow Density Lipoprotein Receptor-Related Protein-6MicePhosphorylationProtein StabilityAXIN1 protein, humanAxin Proteinbeta CateninCarcinogensCasein Kinase 1 epsilonCasein Kinase IdeltaCTNNB1 protein, humanLow Density Lipoprotein Receptor-Related Protein-6LRP6 protein, humanPurinesSR-3029TCF4 protein, humanTetradecanoylphorbol AcetateTranscription Factor 4Wnt ProteinsCK1LRP6TPAtwo-stage skin chemical carcinogenesisWnt/β-catenin signaling

Identifiers

PMID30038030
PMCPMC6094128
OpenAlexW2884265136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.