Evidence map›Paper›PMID 30038013›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Recombinant

Weiwen Deng, Victor Lira, Thomas E Hudson, Edward E Lemmens, William G Hanson, Ruben Flores, Gonzalo Barajas, George E Katibah, Anthony L Desbien, Peter Lauer and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Living Microbial Drugs.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  3. Avoidance of MAIT cells is an essential determinant ofProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. ReprogrammingmBio · 2026
    Article
  5. Microbiota in cancer: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Infection and immunity · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Recent Advances in Host Immune Mechanisms AgainstJournal of inflammation research · 2025
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Weiwen DengAduro Biotech, Inc., Berkeley, CA 94710; wdeng@aduro.com tdubensky@tempesttx.com.
Victor LiraAduro Biotech, Inc., Berkeley, CA 94710.
Thomas E HudsonAduro Biotech, Inc., Berkeley, CA 94710.
Edward E LemmensAduro Biotech, Inc., Berkeley, CA 94710.
William G HansonAduro Biotech, Inc., Berkeley, CA 94710.
Ruben FloresAduro Biotech, Inc., Berkeley, CA 94710.
Gonzalo BarajasAduro Biotech, Inc., Berkeley, CA 94710.
George E KatibahAduro Biotech, Inc., Berkeley, CA 94710.
Anthony L DesbienAduro Biotech, Inc., Berkeley, CA 94710.
Peter LauerAduro Biotech, Inc., Berkeley, CA 94710.
Meredith L LeongAduro Biotech, Inc., Berkeley, CA 94710.
Daniel A PortnoyDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Thomas W DubenskyAduro Biotech, Inc., Berkeley, CA 94710; wdeng@aduro.com tdubensky@tempesttx.com.
Aduro BioTech (United States) · USUniversity of California, Berkeley · US

Funding

The role of Listeria cyclic-di-AMP during infection and immunityP01AI063302 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI STANLEY, SARAH A · 2004 to 2025
$45.5M
Listeria Hemolysis and Escape From a VacuoleR01AI027655 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI DANIEL A PORTNOY · 1993 to 2026
$10.1M
NIAID NIH HHS P01 AI063302NIAID NIH HHS R01 AI027655
6 · The paper itself

Abstract

Agents that remodel the tumor microenvironment (TME), prime functional tumor-specific T cells, and block inhibitory signaling pathways are essential components of effective immunotherapy. We are evaluating live-attenuated, double-deleted

Indexed as

AnimalsAntigens, NeoplasmCancer VaccinesCD8-Positive T-LymphocytesCell Line, TumorDrug Evaluation, PreclinicalFemaleHumansListeria monocytogenesMacrophagesMiceMice, Inbred BALB CMice, Inbred C57BLNeoplasmsTreatment OutcomeTumor MicroenvironmentAntigens, NeoplasmCancer VaccinesVaccines, AttenuatedVaccines, DNAcancer vaccineCD8+ TListeria monocytogenestumor microenvironment

Identifiers

PMID30038013
PMCPMC6094133
OpenAlexW2883484901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.