Evidence map›Paper›PMID 30038008›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Analysis of CD8

Saori Sakabe, Brian M Sullivan, Jessica N Hartnett, Refugio Robles-Sikisaka, Karthik Gangavarapu, Beatrice Cubitt, Brian C Ware, Dylan Kotliar, Luis M Branco, Augustine Goba and 10 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Newly identified oncolytic VSV-GP-specific CD8Molecular therapy. Oncology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Self-amplifying RNA vaccine protects mice against lethal Ebola virus infection.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. EnhancedJournal of virology · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 2 countries.

Saori SakabeViral-Immunobiology Laboratory, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Brian M SullivanViral-Immunobiology Laboratory, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037; bsully@scripps.edu mbaobo@scripps.edu.
Jessica N HartnettDepartment of Immunology and Microbiology, Tulane University School of Medicine, New Orleans, LA 70112.
Refugio Robles-SikisakaViral-Immunobiology Laboratory, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Karthik GangavarapuDepartment of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037.
Beatrice CubittViral-Immunobiology Laboratory, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Brian C WareViral-Immunobiology Laboratory, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Dylan KotliarFAS Center for Systems Biology, Harvard University Medical School and The Broad Institute of Massachusetts Institute of Technology, Boston, MA 02142.
Luis M BrancoZalgen Labs, Germantown, MD 20876.
Augustine GobaViral Hemorrhagic Fever Program, Kenema Government Hospital, Kenema, Sierra Leone.
Mambu MomohViral Hemorrhagic Fever Program, Kenema Government Hospital, Kenema, Sierra Leone.
John Demby SandiViral Hemorrhagic Fever Program, Kenema Government Hospital, Kenema, Sierra Leone.
Lansana KannehViral Hemorrhagic Fever Program, Kenema Government Hospital, Kenema, Sierra Leone.
Donald S GrantViral Hemorrhagic Fever Program, Kenema Government Hospital, Kenema, Sierra Leone.
Robert F GarryDepartment of Immunology and Microbiology, Tulane University School of Medicine, New Orleans, LA 70112.ORCID 0000-0002-5683-3250
Kristian G AndersenViral-Immunobiology Laboratory, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Juan Carlos de la TorreViral-Immunobiology Laboratory, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Pardis C SabetiFAS Center for Systems Biology, Harvard University Medical School and The Broad Institute of Massachusetts Institute of Technology, Boston, MA 02142.
John S SchieffelinDepartment of Pediatrics, Tulane University School of Medicine, New Orleans, LA 70112.
Michael B A OldstoneViral-Immunobiology Laboratory, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037; bsully@scripps.edu mbaobo@scripps.edu.ORCID 0000-0003-0804-0501
Scripps Research Institute · USUniversity of Sierra Leone · SLTulane University · USBroad Institute · USZalgen (United States) · US

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Technology CoreU19AI135995 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI Kristian Graugaard Andersen · 2018 to 2026
$32.0M
NIAID NIH HHS HHSN272201400048CNIAID NIH HHS U19 AI135995NIGMS NIH HHS T32 GM007753
6 · The paper itself

Abstract

The recent Ebola epidemic exemplified the importance of understanding and controlling emerging infections. Despite the importance of T cells in clearing virus during acute infection, little is known about Ebola-specific CD8

Indexed as

EpidemicsAdolescentAdultAntibodies, ViralAntigens, ViralCD8-Positive T-LymphocytesEbolavirusEpitopes, T-LymphocyteFemaleHemorrhagic Fever, EbolaHLA AntigensHumansMaleNucleoproteinsSierra LeoneSurvivorsAntibodies, ViralAntigens, ViralEpitopes, T-LymphocyteHLA AntigensNucleoproteinsViral ProteinsCD8 T cellsEbolaepitopesHLAvirus-specific

Identifiers

PMID30038008
PMCPMC6094108
OpenAlexW2883446746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.