Evidence map›Paper›PMID 30037972›Full record

ArticlePediatrics2018

Food Additives and Child Health.

Leonardo Trasande, Rachel M Shaffer, Sheela Sathyanarayana, COUNCIL ON ENVIRONMENTAL HEALTH

Abstract read
In one paragraph

Article in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Reverse-engineered exclusive enteral nutrition as induction therapy in pediatric Crohn's disease: Effects on environmental toxin exposure.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2026
    Article
  6. Review
  7. Article
  8. Endolysin-based biocontrol strategies againstFood science and biotechnology · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Leonardo Trasande
Rachel M Shaffer
Sheela Sathyanarayana
COUNCIL ON ENVIRONMENTAL HEALTH

Funding

The NYU Children’s Health & Environment Study: an ECHO CohortUG3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRASANDE, LEONARDO · 2016 to 2024
$26.5M
Biostatistics, Epidemiologic & Bioinformatic Training in Environmental HealthT32ES015459 · NIEHS · UNIVERSITY OF WASHINGTON · PI June T. Spector · 2009 to 2026
$10.6M
Phthalates, BPA, Trajectories of In and Ex Utero Growth and Cardiometabolic RisksR01ES022972 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRASANDE, LEONARDO · 2014 to 2018
$2.7M
Environmental Oxidant Stressors in Pediatric Chronic Kidney Disease - ResubmissioR01DK100307 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRACHTMAN, HOWARD, TRASANDE, LEONARDO · 2014 to 2018
$2.5M
Prenatal WTC Chemical Exposures, Birth Outcomes and Cardiometabolic Risks-Resubmission-1U01OH011299 · OH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HERBSTMAN, JULIE BETH, TRASANDE, LEONARDO · 2017 to 2020
$2.4M
Prenatal & Childhood POP Exposures, Obesity & Cardiovascular Risks in Children -Resubmission-1R56ES027256 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MESSITO, MARY J, TRASANDE, LEONARDO · 2017 to 2017
$297k
NIDDK NIH HHS R01 DK100307NIEHS NIH HHS R01 ES022972NIEHS NIH HHS R56 ES027256NIEHS NIH HHS T32 ES015459NIH HHS UG3 OD023305NIOSH CDC HHS U01 OH011299
6 · The paper itself

Abstract

Increasing scientific evidence suggests potential adverse effects on children's health from synthetic chemicals used as food additives, both those deliberately added to food during processing (direct) and those used in materials that may contaminate food as part of packaging or manufacturing (indirect). Concern regarding food additives has increased in the past 2 decades in part because of studies that increasingly document endocrine disruption and other adverse health effects. In some cases, exposure to these chemicals is disproportionate among minority and low-income populations. This report focuses on those food additives with the strongest scientific evidence for concern. Further research is needed to study effects of exposure over various points in the life course, and toxicity testing must be advanced to be able to better identify health concerns prior to widespread population exposure. The accompanying policy statement describes approaches policy makers and pediatricians can take to prevent the disease and disability that are increasingly being identified in relation to chemicals used as food additives, among other uses.

Indexed as

Health PolicyAcademies and InstitutesChildChild HealthFood AdditivesHumansFood Additives

Identifiers

PMID30037972
PMCPMC6298598

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.