Evidence map›Paper›PMID 30037968›Full record

ReviewCold Spring Harbor perspectives in biology2019

The Epitranscriptome in Translation Regulation.

Eyal Peer, Sharon Moshitch-Moshkovitz, Gideon Rechavi, Dan Dominissini

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. The Role of RNA Modification in HIV-1 Infection.International journal of molecular sciences · 2022
    Review
  10. RNA methyltransferase METTL16: Targets and function.Wiley interdisciplinary reviews. RNA · 2022
    Review
  11. Article
  12. Metabolic Signatures of Life Span Regulated by Mating, Sex Peptide, and Mifepristone/RU486 in Female Drosophila melanogaster.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  13. Reprogramming of mRNA biology · 2021
    Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. The mNature reviews. Neuroscience · 2020
    Review
  19. Protein Synthesis and Translational Control: A Historical Perspective.Cold Spring Harbor perspectives in biology · 2019
    Review
  20. Principles of Translational Control.Cold Spring Harbor perspectives in biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Eyal PeerSackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel; Cancer Research Center and Wohl Centre for Translational Medicine, Chaim Sheba Medical Center, Tel-Hashomer 5262160, Israel.
Sharon Moshitch-MoshkovitzSackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel; Cancer Research Center and Wohl Centre for Translational Medicine, Chaim Sheba Medical Center, Tel-Hashomer 5262160, Israel.
Gideon RechaviSackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel; Cancer Research Center and Wohl Centre for Translational Medicine, Chaim Sheba Medical Center, Tel-Hashomer 5262160, Israel.
Dan DominissiniSackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel; Cancer Research Center and Wohl Centre for Translational Medicine, Chaim Sheba Medical Center, Tel-Hashomer 5262160, Israel.
Sheba Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cellular proteome reflects the total outcome of many regulatory mechanisms that affect the metabolism of messenger RNA (mRNA) along its pathway from synthesis to degradation. Accumulating evidence in recent years has uncovered the roles of a growing number of mRNA modifications in every step along this pathway, shaping translational output. mRNA modifications affect the translation machinery directly, by influencing translation initiation, elongation and termination, or by altering mRNA levels and subcellular localization. Features of modification-related translational control are described, charting a new and complex layer of translational regulation.

Indexed as

EpigenomicsGene Expression RegulationTranscription, GeneticTranscriptomeAdenosineAnimalsCytidineHomeostasisHumansMethylationPeptide Chain Elongation, TranslationalPeptide Chain Initiation, TranslationalProtein BiosynthesisPseudouridineRNA, MessengerRNA, Transfer1-methyladenosine5-hydroxymethylcytidine5-methylcytidineAdenosineCytidineN(6),O(2)-dimethyladenosineN-methyladenosinePseudouridineRNA, MessengerRNA, Transfer

Identifiers

PMID30037968
PMCPMC6671940
OpenAlexW2884137413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.