Evidence map›Paper›PMID 30037903›Full record

ArticleThe Journal of biological chemistry2018

Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells.

Sumeet Poudel, Jianhong Yao, Michael G Kemp, Michael Leffak

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sumeet PoudelFrom the Departments of Biochemistry and Molecular Biology and.
Jianhong YaoFrom the Departments of Biochemistry and Molecular Biology and.
Michael G KempPharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio 45435.ORCID 0000-0001-8203-0745
Michael LeffakFrom the Departments of Biochemistry and Molecular Biology and michael.leffak@wright.edu.
Wright State University · US

Funding

Mechanisms of Replication-Dependent Microsatellite Instability in Human DiseaseR01GM122976 · NIGMS · WRIGHT STATE UNIVERSITY · PI LEFFAK, MICHAEL · 2017 to 2020
$1.2M
Second-site genetic modifiers of CTG/CAG microsatellite stabilityR01GM099874 · NIGMS · WRIGHT STATE UNIVERSITY · PI LEFFAK, MICHAEL · 2012 to 2015
$1.1M
NIGMS NIH HHS R01 GM099874NIGMS NIH HHS R01 GM122976
6 · The paper itself

Abstract

A key step in the initiation of eukaryotic DNA replication is the binding of the activator protein Cdc45 to promote MCM helicase unwinding of the origin template. We show here that the c-

Indexed as

Carrier ProteinsCell CycleCell Cycle ProteinsChromatinDNA-Binding ProteinsDNA DamageDNA ReplicationHeLa CellsHumansMinichromosome Maintenance ProteinsNuclear ProteinsProtein BindingStress, PhysiologicalCarrier ProteinsCDC45 protein, humanCell Cycle ProteinsChromatinDNA-Binding ProteinsDTD1 protein, humanMinichromosome Maintenance ProteinsNuclear ProteinsTICRR protein, humanTOPBP1 protein, humancheckpoint controlchromatin regulationDNA damage responseDNA-protein interactionDNA replication

Identifiers

PMID30037903
PMCPMC6139568
OpenAlexW2883995070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.