Evidence map›Paper›PMID 30037798›Full record

ArticleInfection and immunity2018

Desialylation of Platelets by Pneumococcal Neuraminidase A Induces ADP-Dependent Platelet Hyperreactivity.

Vesla Kullaya, Marien I de Jonge, Jeroen D Langereis, Christa E van der Gaast-de Jongh, Christian Büll, Gosse J Adema, Dirk Lefeber, Amelieke J Cremers, Blandina T Mmbaga, Phillip G de Groot and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Biofilm-dispersed pneumococci induce elevated leukocyte and platelet activation.Frontiers in cellular and infection microbiology · 2024
    Article
  3. International journal of molecular sciences · 2023
    Article
  4. Platelets interact with CD169Frontiers in immunology · 2023
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Role of Pneumococcal NanA Neuraminidase Activity in Peripheral Blood.Frontiers in cellular and infection microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Vesla KullayaDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands vesla.kullaya@radboudumc.nl.
Marien I de JongeRadboud Center for Infectious Diseases, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
Jeroen D LangereisRadboud Center for Infectious Diseases, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0001-5317-3202
Christa E van der Gaast-de JonghRadboud Center for Infectious Diseases, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
Christian BüllDepartment of Radiation Oncology, Radiotherapy and Oncoimmunology Laboratory, Radboud University Medical Center, Nijmegen, The Netherlands.
Gosse J AdemaDepartment of Radiation Oncology, Radiotherapy and Oncoimmunology Laboratory, Radboud University Medical Center, Nijmegen, The Netherlands.
Dirk LefeberTranslational Metabolic Laboratory, Radboud University Medical Center, Nijmegen, The Netherlands.
Amelieke J CremersDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Blandina T MmbagaKilimanjaro Clinical Research Institute, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Phillip G de GrootDepartment of Clinical Chemistry and Haematology, University Medical Centre, Utrecht, The Netherlands.
Quirijn de MastDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Andre J van der VenDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLKilimanjaro Christian Medical Centre · TZUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelets are increasingly recognized to play a role in the complications of

Indexed as

Adenosine DiphosphateBacterial ProteinsBlood PlateletsHost-Pathogen InteractionsHumansN-Acetylneuraminic AcidNeuraminidasePlatelet AggregationPneumococcal InfectionsStreptococcus pneumoniaeAdenosine DiphosphateBacterial ProteinsN-Acetylneuraminic AcidNeuraminidasedesialylationNanAplateletssialic acidStreptococcus pneumoniae

Identifiers

PMID30037798
PMCPMC6204724
OpenAlexW2884390105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.