Evidence map›Paper›PMID 30037791›Full record

ArticleInfection and immunity2018

Mycobacterium tuberculosis Lipoprotein and Lipoglycan Binding to Toll-Like Receptor 2 Correlates with Agonist Activity and Functional Outcomes.

Supriya Shukla, Edward T Richardson, Michael G Drage, W Henry Boom, Clifford V Harding

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. HowVaccines · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Recognition of Mycobacterium tuberculosis by macrophage Toll-like receptor and its role in autophagy.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Review
  14. MedComm · 2024
    Review
  15. Article
  16. Review
  17. Review
  18. Virulence Factors ofPathogens (Basel, Switzerland) · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Supriya ShuklaDepartment of Pathology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Edward T RichardsonDepartment of Pathology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Michael G DrageDepartment of Pathology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
W Henry BoomDepartment of Pathology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Clifford V HardingDepartment of Pathology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA cvh3@cwru.edu.ORCID https://orcid.org/0000-0002-6333-162X
University Hospitals of Cleveland · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4M
Regulation of macrophages by Mycobacterium tuberculosisR01AI034343 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI HARDING, CLIFFORD V · 1994 to 2017
$6.2M
HETEROGENEITY OF TCELLS IN M TUBERCULOSIS INFECTIONR01AI027243 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BOOM, W. HENRY · 1989 to 2016
$5.5M
Immunology Training Program-PredoctoralT32AI089474 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI COBB, BRIAN A · 2010 to 2025
$3.4M
M. tuberculosis lipoprotein-TLR2 interactionsR01AI069085 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI HARDING, CLIFFORD V · 2007 to 2011
$1.9M
NIAID NIH HHS R01 AI027243NIAID NIH HHS R01 AI034343NIAID NIH HHS R01 AI069085NIAID NIH HHS T32 AI089474NIGMS NIH HHS T32 GM007250
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBacterial ProteinsFemaleHumansLipopolysaccharidesLipoproteinsMiceMice, Inbred C57BLMycobacterium tuberculosisProtein BindingSignal TransductionToll-Like Receptor 1Toll-Like Receptor 2TuberculosisBacterial ProteinsLipopolysaccharidesLipoproteinsToll-Like Receptor 1Toll-Like Receptor 2agonistimmune responselipoglycanlipoproteinMycobacterium tuberculosisToll-like receptor (TLR)

Identifiers

PMID30037791
PMCPMC6204744
OpenAlexW2883817407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.