Observational studyJournal of optometry
High-speed recording of thermal load during laser trans-epithelial corneal refractive surgery using a 750Hz ablation system.
Observational study in Journal of optometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 17 citations in OpenAlex.
- Transepithelial Photorefractive Keratectomy-Review.Vision (Basel, Switzerland) · 2024Review
- Advances in Transepithelial Photorefractive Keratectomy versus Laser-Assisted In Situ Keratomileusis.Diagnostics (Basel, Switzerland) · 2024Article
- Assessing the local temperature of human cornea exposed to surface ablation by different laser refractive-surgery devices: a numerical comparative study.Lasers in medical science · 2021Article
- Single-Step Transepithelial Photorefractive Keratectomy in Low to Moderate Myopia: A One-Year Follow-Up Study.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Ocular surgery after herpes simplex and herpes zoster keratitis.International ophthalmology · 2020Review
- [Transepithelial photorefractive keratectomy : Results and clinical experiences].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2019Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the temperature rise of human cornea during trans-epithelial photorefractive keratectomy (trans-PRK) with a 750Hz excimer laser employing Intelligent Thermal Effect Control (ITEC) software.
methodsIn this observational case series, trans-PRK ablation was performed on 5 eyes of 3 patients using an aspheric profile of a 750Hz excimer laser system. A high-resolution infrared camera with a frame-rate of 350 images per second was used to determine the corneal surface temperature. Images were taken sequentially, starting a few seconds prior to and ending a few seconds after the ablation. The maximum temperature of any pixel of a given image were recorded and graphed against time.
resultsThe baseline ocular surface temperature, immediately prior to the beginning of excimer laser, ranged from 32 to 34.9°C. The maximum ocular surface temperature until the epithelium was ablated ranged from 35.2 to 39.7°C. The maximum ocular surface temperature during stromal ablation with high and low fluence laser ranged from 32.9 to 36.5 and from 34.4 to 37.7°C respectively.
conclusionThe ITEC software is effective in controlling the maximum temperature rise during laser ablation in the extremely challenging situation of trans-PRK involving high ablation volumes of almost 6000nl, potentially improving the outcomes. The ITEC system limited the maximum temperature to 39.7°C in the epithelium, and 37.7°C in the stroma. The epithelial temperature was always higher than stromal temperature (regardless of high or low fluence irradiation). Safety limit of 40°C found in the literature was never reached.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.