Evidence map›Paper›PMID 30037342›Full record

ArticleBMC musculoskeletal disorders2018

Effect of local infiltration analgesia, peripheral nerve blocks, general and spinal anesthesia on early functional recovery and pain control in unicompartmental knee arthroplasty.

M T Berninger, J Friederichs, W Leidinger, P Augat, V Bühren, C Fulghum, W Reng

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 55 citations in OpenAlex.

  1. [Fast-Track-Arthroplasty].Orthopadie (Heidelberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

M T Berningerendogap, Joint Replacement Institute, Garmisch-Partenkirchen Medical Center, Auenstr. 6, 82467, Garmisch-Partenkirchen, Germany. Markus.Berninger@bgu-murnau.de.ORCID http://orcid.org/0000-0003-0409-3868
J FriederichsDepartment of Trauma Surgery, BG Trauma Center Murnau, Prof.-Küntscher Str. 8, 82418, Murnau, Germany.
W LeidingerDepartment of Anesthesiology and Intensive Care, Garmisch-Partenkirchen Medical Center, Auenstr. 6, 82467, Garmisch-Partenkirchen, Germany.
P AugatInstitute of Biomechanics, BG Trauma Center Murnau, Prof.-Küntscher Str. 8, 82418, Murnau, Germany.
V BührenDepartment of Trauma Surgery, BG Trauma Center Murnau, Prof.-Küntscher Str. 8, 82418, Murnau, Germany.
C Fulghumendogap, Joint Replacement Institute, Garmisch-Partenkirchen Medical Center, Auenstr. 6, 82467, Garmisch-Partenkirchen, Germany.
W Rengendogap, Joint Replacement Institute, Garmisch-Partenkirchen Medical Center, Auenstr. 6, 82467, Garmisch-Partenkirchen, Germany.
Berufsgenossenschaftliche Unfallklinik Murnau · DEGarmisch-Partenkirchen Medical Center · DEParacelsus Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the study was to analyze the effect of local infiltration analgesia (LIA), peripheral nerve blocks, general and spinal anesthesia on early functional recovery and pain control in primary unicompartmental knee arthroplasty (UKA).

methodsBetween January 2016 until August 2016, 134 patients underwent primary UKA and were subdivided into four groups according to their concomitant pain and anesthetic procedure with catheter-based techniques of femoral and sciatic nerve block (group GA&FNB, n = 38) or epidural catheter (group SP&EPI, n = 20) in combination with general anesthesia or spinal anesthesia, respectively, and LIA combined with general anesthesia (group GA&LIA, n = 46) or spinal anesthesia (group SP&LIA, n = 30). Outcome parameters focused on the evaluation of pain (NRS scores), mobilization, muscle strength and range of motion up to 7 days postoperatively. The cumulative consumption of (rescue) pain medication was analyzed.

resultsThe LIA groups revealed significantly lower (about 50%) mean NRS scores (at rest) compared to the catheter-based groups at the day of surgery. In the early postoperative period, the dose of hydromorphone as rescue pain medication was significantly lower (up to 68%) in patients with SP&EPI compared to all other groups. No significant differences could be detected with regard to grade of mobilization, muscle strength and range of motion. However, there seemed to be a trend towards improved mobilization and muscle strength with general anesthesia and LIA, whereof general anesthesia generally tended to ameliorate mobilization.

conclusionsExcept for a significant lower NRS score at rest in the LIA groups at day of surgery, pain relief was comparable in all groups without clinically relevant differences, while the use of opioids was significantly lower in patients with SP&EPI. A clear clinically relevant benefit for LIA in UKA cannot be stated. However, LIA offers a safe and effective treatment option comparable to the well-established conventional procedures.

Indexed as

AgedAged, 80 and overAnesthesia, GeneralAnesthesia, LocalAnesthesia, SpinalAnesthetics, LocalArthroplasty, Replacement, KneeAutonomic Nerve BlockFemaleHumansMaleMiddle AgedOsteoarthritis, KneePain ManagementPostoperative PainRecovery of FunctionAnesthetics, LocalEpidural catheterFemoral nerve blockGeneral anesthesiaLocal infiltration analgesiaSpinal anesthesiaUnicompartmental knee arthroplasty

Identifiers

PMID30037342
PMCPMC6056928
OpenAlexW2884322227

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.