ArticleBiomolecules2018
Adverse Outcome Prediction of Iron Deficiency in Patients with Acute Coronary Syndrome.
Article in Biomolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 62 citations in OpenAlex.
- Intravenous ferric carboxymaltose in heart failure with iron deficiency (FAIR-HF2 DZHK05 trial): Sex-specific outcomes.European journal of heart failure · 2025Trial
- Admission ferritin in STEMI predicts long-term major adverse cardiovascular outcomes.European heart journal open · 2026Article
- Iron Deficiency in Acute Coronary Syndrome Treated with Percutaneous Angioplasty-A Factor of Unestablished Significance.Biomedicines · 2026Article
- Underlying Mechanisms of Osteoporosis in the Context of Multimorbidity: Clinical Challenges and Management Strategies.Nutrients · 2026Review
- Circulating protein biomarkers and their association with vulnerable plaque characteristics - a PROSPECT II substudy.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Iron Deficiency Is Associated With Impaired Myocardial Reperfusion in ST-Segment-Elevation Myocardial Infarction: Influence of the Definition Used.Journal of the American Heart Association · 2025Article
- Impact of Hemoglobin and Iron Deficiency on Mortality in Patients with Acute Myocardial Infarction in Intensive Care Units: A Retrospective Study from MIMIC-IV.Reviews in cardiovascular medicine · 2025Article
- Iron Deficiency as a Factor of Worse Prognosis in Patients with Acute Myocardial Infarction.Biomedicines · 2025Review
- Effect of iron status on myocardial infarction: A two-sample Mendelian randomization study.Heliyon · 2024Article
- Association of Iron Therapy with Mortality in Patients with Acute Myocardial Infarction and Iron Deficiency.Cardiovascular toxicology · 2024Article
- Iron Deficiency Might Impair the Recovery of Left Ventricular Function after Surgical Revascularization in Diabetic Patients: A Retrospective Study.Reviews in cardiovascular medicine · 2023Article
- Role of Iron Deficiency in Heart Failure-Clinical and Treatment Approach: An Overview.Diagnostics (Basel, Switzerland) · 2023Review
- Mendelian randomization study reveals a causal relationship between serum iron status and coronary heart disease and related cardiovascular diseases.Frontiers in cardiovascular medicine · 2023Article
- Iron deficiency and cardiovascular disease.European heart journal · 2023Article
- Can Iron Play a Crucial Role in Maintaining Cardiovascular Health in the 21st Century?International journal of environmental research and public health · 2022Review
- Short-term treatment of iron deficiency anemia after cardiac surgery.International journal of cardiology. Heart & vasculature · 2022Article
- Effects of Iron Supplementation on Testicular Function and Spermatogenesis of Iron-Deficient Rats.Nutrients · 2022Article
- Acute heart failure and iron deficiency: a prospective, multicentre, observational study.ESC heart failure · 2022Observational
- Association of iron deficiency with incident cardiovascular diseases and mortality in the general population.ESC heart failure · 2021Article
- Low testosterone concentrations and prediction of future heart failure in men and in women: evidence from the large FINRISK97 study.ESC heart failure · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute myocardial infarction remains a leading cause of morbidity and mortality. While iron deficient heart failure patients are at increased risk of future cardiovascular events and see improvement with intravenous supplementation, the clinical relevance of iron deficiency in acute coronary syndrome remains unclear. We aimed to evaluate the prognostic value of iron deficiency in the acute coronary syndrome (ACS). Levels of ferritin, iron, and transferrin were measured at baseline in 836 patients with ACS. A total of 29.1% was categorized as iron deficient. The prevalence of iron deficiency was clearly higher in women (42.8%), and in patients with anemia (42.5%). During a median follow-up of 4.0 years, 111 subjects (13.3%) experienced non-fatal myocardial infarction (MI) and cardiovascular mortality as combined endpoint. Iron deficiency strongly predicted non-fatal MI and cardiovascular mortality with a hazard ratio (HR) of 1.52 (95% confidence interval (CI) 1.03-2.26;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.