Evidence map›Paper›PMID 30036991›Full record

ArticleInternational journal of molecular sciences2018

Functional Characterization and Structure-Guided Mutational Analysis of the Transsulfuration Enzyme Cystathionine γ-Lyase from

Elena Maresi, Giacomo Janson, Silvia Fruncillo, Alessandro Paiardini, Rosario Vallone, Paola Dominici, Alessandra Astegno

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Structural insight into the unique conformation of cystathionine β-synthase fromComputational and structural biotechnology journal · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elena MaresiDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy. elena.maresi@univr.it.
Giacomo JansonDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy. giacomo.janson@uniroma1.it.
Silvia FruncilloDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy. silvia.fruncillo@univr.it.
Alessandro PaiardiniDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy. alessandro.paiardini@uniroma1.it.
Rosario ValloneDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy. rosario.vallone@univr.it.
Paola DominiciDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy. paola.dominici@univr.it.
Alessandra AstegnoDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy. alessandra.astegno@univr.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sulfur-containing amino acids play essential roles in many organisms. The protozoan parasite

Indexed as

CystathionineCystathionine gamma-LyaseDNA Mutational AnalysisMutationPhosphoric Monoester HydrolasesToxoplasmaCystathionineCystathionine gamma-LyasePhosphoric Monoester Hydrolasespyridoxal-5-phosphatasecystathionine γ-lyasepyridoxal-5′-phosphatereaction specificityreverse transsulfuration pathwayToxoplasma gondii

Identifiers

PMID30036991
PMCPMC6073527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.