Evidence map›Paper›PMID 30036566›Full record

ReviewBiochimica et biophysica acta. Molecular cell research2019

Protein phosphatases in chromatin structure and function.

Raquel Sales Gil, Paola Vagnarelli

Open access · hybridAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta. Molecular cell research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Raquel Sales GilColleges of Health and Life Science, Research Institute for Environment Health and Society, Brunel University London, London UB8 3PH, UK.
Paola VagnarelliColleges of Health and Life Science, Research Institute for Environment Health and Society, Brunel University London, London UB8 3PH, UK. Electronic address: Paola.Vagnarelli@Brunel.ac.uk.
Brunel University of London · GB

Funding

Biotechnology and Biological Sciences Research Council BB/K017632/1Wellcome TrustWellcome Trust 210742/Z/18/Z
6 · The paper itself

Abstract

Chromatin structure and dynamics are highly controlled and regulated processes that play an essential role in many aspects of cell biology. The chromatin transition stages and the factors that control this process are regulated by post-translation modifications, including phosphorylation. While the role of protein kinases in chromatin dynamics has been quite well studied, the nature and regulation of the counteracting phosphatases represent an emerging field but are still at their infancy. In this review we summarize the current literature on phosphatases involved in the regulation of chromatin structure and dynamics, with emphases on the major knowledge gaps that should require attention and more investigation.

Indexed as

AnimalsChromatinChromatin Assembly and DisassemblyDNADNA MethylationDNA RepairDNA ReplicationEpigenesis, GeneticGene Expression RegulationHistonesHumansNucleosomesPhosphoprotein PhosphatasesPhosphorylationProtein Processing, Post-TranslationalTelomereChromatinDNAHistonesNucleosomesPhosphoprotein PhosphatasesChromatin remodellingEpigeneticsHistone phosphorylationPhosphatasesTranscription regulation

Identifiers

PMID30036566
PMCPMC6227384
OpenAlexW2884901523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.