ArticleImmunoHorizons2017
The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4
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In one paragraph
Article in ImmunoHorizons, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 21 citations in OpenAlex.
- Mechanism of RNA-Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis.The Kaohsiung journal of medical sciences · 2026Article
- HuR ablation destabilizesFrontiers in immunology · 2025Article
- Epigenetic factors and inflammaging: FOXO3A as a potential biomarker of sarcopenia and upregulation of DNMT3A and SIRT3 in older adults.Frontiers in immunology · 2025Article
- Human IL-17A protein production is controlled through a PIP5K1α-dependent translational checkpoint.Science signaling · 2023Article
- Niclosamide improves cancer immunotherapy by modulating RNA-binding protein HuR-mediated PD-L1 signaling.Cell & bioscience · 2023Article
- Post-transcriptional checkpoints in autoimmunity.Nature reviews. Rheumatology · 2023Review
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Exploration and Validation of Potential Biomarkers and Therapeutic Targets in Ferroptosis of Asthma.Journal of asthma and allergy · 2023Article
- RNA Metabolism in T Lymphocytes.Immune network · 2022Review
- Post-transcriptional control of T-cell cytokine production: Implications for cancer therapy.Immunology · 2021Review
- HuR Plays a Positive Role to Strengthen the Signaling Pathways of CD4Journal of immunology research · 2021Article
- mRNA Post-Transcriptional Regulation by AU-Rich Element-Binding Proteins in Liver Inflammation and Cancer.International journal of molecular sciences · 2020Review
- RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity.Science advances · 2020Article
- RNA-Binding Protein HuR Promotes Th17 Cell Differentiation and Can Be Targeted to Reduce Autoimmune Neuroinflammation.Journal of immunology (Baltimore, Md. : 1950) · 2020Article
- HuR controls apoptosis and activation response without effects on cytokine 3' UTRs.RNA biology · 2019Article
- Article
- RNA-binding proteins control gene expression and cell fate in the immune system.Nature immunology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 3 institutions in 1 country.
Patsharaporn TechasintanaDepartment of Surgery, University of Missouri, Columbia, MO 65212.
Jason S EllisDepartment of Surgery, University of Missouri, Columbia, MO 65212.
Jacqueline GlascockDepartment of Surgery, University of Missouri, Columbia, MO 65212.
Matthew M GubinDepartment of Surgery, University of Missouri, Columbia, MO 65212.
Suzanne E RidenhourDepartment of Surgery, University of Missouri, Columbia, MO 65212.
Joseph D MageeDepartment of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO 65212.
Marcia L HartDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65201.
Peng YaoDepartment of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195.
Hao ZhouDepartment of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195.
Maryln S WhitneyDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65201.
Craig L FranklinDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65201.
Jennifer L MartindaleLaboratory of Genetics and Genomics, National Institute on Aging, Baltimore, MD 21224.
Myriam GorospeLaboratory of Genetics and Genomics, National Institute on Aging, Baltimore, MD 21224.
Wade J DavisDepartment of Biostatistics, University of Missouri, Columbia, MO 65212.
Paul L FoxDepartment of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195.
Xiaoxia LiDepartment of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195.
Ulus AtasoyDepartment of Surgery, University of Missouri, Columbia, MO 65212.
University of Missouri · USCleveland Clinic · USInstitute on Aging · US
Funding
TELOMERASE INACTIVATION BY RNASE L SIGNALS CELL DEATHP01CA062220 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI LI, XIAOXIA, STARK, GEORGE ROBERT · 1994 to 2020
$35.6MPost-transcriptional Regulation Of Proliferative and Stress Response GenesZIAAG000511 · NIA · NATIONAL INSTITUTE ON AGING · PI GOROSPE, MYRIAM · 2009 to 2025
$25.4MThe Mutant Mouse Resource and Research Center at the University of Missouri - ResourceU42OD010918 · OD · UNIVERSITY OF MISSOURI-COLUMBIA · PI James Amos-Landgraf · 2012 to 2026
$25.1MInfluence of Post-transcriptional Gene Regulation on Cell Senescence and AgingZIAAG000393 · NIA · NATIONAL INSTITUTE ON AGING · PI GOROSPE, MYRIAM · 2009 to 2025
$24.1MHuR in Allergic Asthma and T Cell DifferentiationR01AI080870 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI ATASOY, ULUS · 2009 to 2019
$3.6MPostdoctoral Training in Comparative MedicineT32OD011126 · OD · UNIVERSITY OF MISSOURI-COLUMBIA · PI Elizabeth C Bryda, Aaron Ericsson · 2012 to 2026
$3.4MPosttranscriptional Gene Regulation in AsthmaR21AI079341 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI ATASOY, ULUS · 2009 to 2010
$381kNCI NIH HHS P01 CA062220NIAID NIH HHS R01 AI080870NIAID NIH HHS R21 AI079341NIH HHS T32 OD011126NIH HHS U42 OD010918
Abstract
Posttranscriptional gene regulation by RNA-binding proteins, such as HuR (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.