Evidence map›Paper›PMID 30035154›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2018

DeepLesion: automated mining of large-scale lesion annotations and universal lesion detection with deep learning.

Ke Yan, Xiaosong Wang, Le Lu, Ronald M Summers

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Automated lesion tracking and treatment response classification on [European journal of nuclear medicine and molecular imaging · 2026
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84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ke YanNational Institutes of Health, Clinical Center, Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Bethesda, Maryland, United States.
Xiaosong WangNational Institutes of Health, Clinical Center, Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Bethesda, Maryland, United States.ORCID https://orcid.org/0000-0002-3840-5658
Le LuNational Institutes of Health, Clinical Center, Clinical Image Processing Service, Radiology and Imaging Sciences, Bethesda, Maryland, United States.
Ronald M SummersNational Institutes of Health, Clinical Center, Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Bethesda, Maryland, United States.ORCID https://orcid.org/0000-0002-0034-9013

Funding

Computer Aided Detection for Radiologic ImagesZIACL040004 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2009 to 2025
$0k
6 · The paper itself

Abstract

Extracting, harvesting, and building large-scale annotated radiological image datasets is a greatly important yet challenging problem. Meanwhile, vast amounts of clinical annotations have been collected and stored in hospitals' picture archiving and communication systems (PACS). These types of annotations, also known as bookmarks in PACS, are usually marked by radiologists during their daily workflow to highlight significant image findings that may serve as reference for later studies. We propose to mine and harvest these abundant retrospective medical data to build a large-scale lesion image dataset. Our process is scalable and requires minimum manual annotation effort. We mine bookmarks in our institute to develop DeepLesion, a dataset with 32,735 lesions in 32,120 CT slices from 10,594 studies of 4,427 unique patients. There are a variety of lesion types in this dataset, such as lung nodules, liver tumors, enlarged lymph nodes, and so on. It has the potential to be used in various medical image applications. Using DeepLesion, we train a universal lesion detector that can find all types of lesions with one unified framework. In this challenging task, the proposed lesion detector achieves a sensitivity of 81.1% with five false positives per image.

Indexed as

bookmarkconvolutional neural networkdeep learninglesion detectionmedical image datasetpicture archiving and communication system

Identifiers

PMID30035154
PMCPMC6052252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.