Evidence map›Paper›PMID 30035118›Full record

ArticleBioMed research international2018

Cardiac Magnetic Resonance in Stable Coronary Artery Disease: Added Prognostic Value to Conventional Risk Profiling.

Oronzo Catalano, Guido Moro, Alessia Mori, Mariarosa Perotti, Alessandra Gualco, Mauro Frascaroli, Clara Pesarin, Carlo Napolitano, Ntobeko A B Ntusi, Silvia G Priori

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. [A review on cardiac positron emission tomography/magnetic resonance imaging in diagnosis of cardivascular diseases].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Oronzo CatalanoDivision of Cardiology, Istituti Clinici Scientifici Maugeri, Pavia, Italy.ORCID 0000-0003-0826-6113
Guido MoroDivision of Radiology, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
Alessia MoriOccupational Medicine Unit, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
Mariarosa PerottiDivision of Cardiology, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
Alessandra GualcoDivision of Cardiology, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
Mauro FrascaroliDivision of Radiology, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
Clara PesarinDivision of Radiology, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
Carlo NapolitanoMolecular Cardiology, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
Ntobeko A B NtusiDepartment of Medicine, Cape Universities Body Imaging Centre, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Silvia G PrioriDivision of Cardiology, Molecular Cardiology, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
Istituti Clinici Scientifici Maugeri · ITUniversity of Cape Town · ZAUniversity of Pavia · IT

Funding

Medical Research Council MC_PC_16096
6 · The paper itself

Abstract

aimsCardiovascular magnetic resonance

methodsWe performed a single centre, observational prospective study that enrolled 465 CAD patients (80% males; 63±11 years), optimally treated with ACE-inhibitors/ARB, aspirin, and statins (76-85%). Assessments included conventional evaluation (clinical history, atherosclerosis RF, electrocardiography, and echocardiography) and a comprehensive CMR with LV dimensions/function, late gadolinium enhancement (LGE), and stress perfusion CMR (SPCMR).

resultsDuring a median follow-up of 62 months (IQR 23-74) there were 50 deaths and 92 major adverse cardiovascular events (MACE). CMR variables improved multivariate model prediction power of mortality and MACE over traditional RF alone (F-test p<0.05 and p<0.001, respectively). LGE was an independent prognostic factor of mortality (hazard ratio [95% CI]: 3.4 [1.3-8.8]); moreover, LGE (3.3 [1.7-6.3]) and SPCMR (2.1 [1.4-3.2]) were the best predictors of MACE.

conclusionLGE is an independent noninvasive marker of mortality in the long term in patients with stable CAD and optimized medical therapy. Furthermore, LGE and SPCMR independently predict MACE beyond conventional risk stratification.

Indexed as

Magnetic Resonance Imaging, CineAgedContrast MediaCoronary Artery DiseaseFemaleHumansMagnetic Resonance SpectroscopyMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesContrast Media

Identifiers

PMID30035118
PMCPMC6032669
OpenAlexW2808974993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.