ArticleJournal of orthopaedic translation2016
Covalently immobilised type I collagen facilitates osteoconduction and osseointegration of titanium coated implants.
Article in Journal of orthopaedic translation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 53 citations in OpenAlex.
- Characterization of Immunogenicity Associated with the Biocompatibility of Type I Collagen from Tilapia Fish Skin.Polymers · 2022Article
- Construction of Local Drug Delivery System on Titanium-Based Implants to Improve Osseointegration.Pharmaceutics · 2022Review
- Combining Sandblasting, Alkaline Etching, and Collagen Immobilization to Promote Cell Growth on Biomedical Titanium Implants.Polymers · 2021Article
- Review of the Applications of Biomedical Compositions Containing Hydroxyapatite and Collagen Modified by Bioactive Components.Materials (Basel, Switzerland) · 2021Review
- Spectroscopic Methods Used in Implant Material Studies.Molecules (Basel, Switzerland) · 2020Review
- Powder metallurgical Ti-Mg metal-metal composites facilitate osteoconduction and osseointegration for orthopedic application.Bioactive materials · 2019Article
- Biomimetic Surfaces Coated with Covalently Immobilized Collagen Type I: An X-Ray Photoelectron Spectroscopy, Atomic Force Microscopy, Micro-CT and Histomorphometrical Study in Rabbits.International journal of molecular sciences · 2019Article
- Customizable Implant-specific and Tissue-Specific Extracellular Matrix Protein Coatings Fabricated Using Atmospheric Plasma.Frontiers in bioengineering and biotechnology · 2019Article
- An in vivo study on the effect of coating stability on osteointegration performance of collagen/hyaluronic acid multilayer modified titanium implants.Bioactive materials · 2018Article
- Translational study of orthopaedic biomaterials and devices.Journal of orthopaedic translation · 2016Article
- Cytocompatibility with osteogenic cells and enhanced in vivo anti-infection potential of quaternized chitosan-loaded titania nanotubes.Bone research · 2016Article
- Osseointegration of nanohydroxyapatite- or nano-calcium silicate-incorporated polyetheretherketone bioactive composites in vivo.International journal of nanomedicineArticle
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivePlasma-sprayed titanium coating (TC) with rough surfaces has been successfully applied in hip or knee prostheses. This study aimed to investigate the osteoconduction and osseointegration of Type I collagen covalently immobilised on TC (TC-AAC) compared with those of TC.
methods
resultsCollagen immobilised on TC could promote hMSCs' migration into the porous structure of the TC. Micro computed tomography images showed that bone trabeculae were significantly more abundant around TC-AAC implants than around TC implants. Fluorescence micrographs indicated more active new-bone formation around implants in the TC-AAC group than in the TC group. The measurement of bone-implant contact on histological sections indicated significantly greater osteointegration around TC-AAC implants than around TC ones.
conclusionImmobilised Type I collagen could improve the osteoconduction and osseointegration of TC implants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.