ArticleJournal of orthopaedic translation2018
Are patients with knee osteoarthritis and patients with knee joint replacement as physically active as healthy persons?
Article in Journal of orthopaedic translation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Amount and type of physical activity and sports from one year forward after hip or knee arthroplasty-A systematic review.PloS one · 2021Pooled it
- Trial
- The Effects of Pedaling-Based Progressive Resistance Training on Range of Motion, Muscle Strength, and Physical Function in Female Patients with Total Knee Arthroplasty: Single-Blind Randomized Controlled Trial.Medicina (Kaunas, Lithuania) · 2025Trial
- Movement smoothness and plasma proteomics are associated with functional impairment in knee osteoarthritis.Osteoarthritis and cartilage open · 2026Article
- Step count as a digital mobility outcome in orthopedics and orthopedic trauma surgery: a scoping review.EFORT open reviews · 2026Review
- Proteomic analysis reveals biomarkers associated with performance-based joint function and patient-reported outcomes in knee osteoarthritis.Osteoarthritis and cartilage open · 2025Article
- Knee osteoarthritis pendulum therapy:Journal of orthopaedic translation · 2024Article
- Postoperative Activity and Knee Function of Patients after Total Knee Arthroplasty: A Sensor-Based Monitoring Study.Journal of personalized medicine · 2023Article
- Bone marrow stem cells incubated with ellipticine regenerate articular cartilage by attenuating inflammation and cartilage degradation in rabbit model.Journal of veterinary science · 2023Article
- Advances in the application of wearable sensors for gait analysis after total knee arthroplasty: a systematic review.Arthroplasty (London, England) · 2023Review
- Antioxidant PDA-PEG nanoparticles alleviate early osteoarthritis by inhibiting osteoclastogenesis and angiogenesis in subchondral bone.Journal of nanobiotechnology · 2022Article
- Monitoring Physical Behavior in Rehabilitation Using a Machine Learning-Based Algorithm for Thigh-Mounted Accelerometers: Development and Validation Study.JMIR bioinformatics and biotechnology · 2022Article
- Factors Affecting Physical Activity of People with Knee Osteoarthritis in Southern Taiwan: A Multiple Logistic Regression Analysis.International journal of clinical practice · 2022Article
- Objectively Measured Physical Activity, Sedentary Behavior and Functional Performance before and after Lower Limb Joint Arthroplasty: A Systematic Review with Meta-Analysis.Journal of clinical medicine · 2021Review
- Applications of Wearable Technology in a Real-Life Setting in People with Knee Osteoarthritis: A Systematic Scoping Review.Journal of clinical medicine · 2021Article
- Should We Use Unilateral or Bilateral Tasks to Assess Maximal and Explosive Knee Extensor Strength in Patients with Knee Osteoarthritis? A Cross-Sectional Study.Journal of clinical medicine · 2021Article
- Remote Patient Monitoring with Wearable Sensors Following Knee Arthroplasty.Sensors (Basel, Switzerland) · 2021Article
- BMSC-Derived Exosomes Ameliorate Osteoarthritis by Inhibiting Pyroptosis of Cartilage via Delivering miR-326 Targeting HDAC3 and STAT1//NF-Mediators of inflammation · 2021Article
- Isokinetic Strength Test of Muscle Strength and Motor Function in Total Knee Arthroplasty.Orthopaedic surgery · 2020Article
- Current clinical utilisation of wearable motion sensors for the assessment of outcome following knee arthroplasty: a scoping review.BMJ open · 2019Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is well documented that patients with knee osteoarthritis (KOA) suffer from reduced physical function and that function of the affected knee is improved after knee joint replacement (KJR). However, it remains uncertain whether patients with KOA are less physically active than healthy people and whether patients increase their level of physical activity after surgery to a level comparable with that of healthy people. The aim of this study was to examine whether patients with KOA are less physically active than healthy participants and whether patients who have undergone KJR show an increased activity and achieve the same level of physical activity as healthy participants 5 years postoperatively.
methodsFifty-four patients with KOA (29 women; mean age 62 ± 8.6; mean body mass index (BMI) 27 ± 5), 52 patients who had KJR due to KOA 5 years earlier (26 women; mean age 66 ± 7.2; mean BMI 30 ± 5) and 171 healthy participants (76 women, mean age 64 ± 9.7, mean BMI 26 ± 5) were included in this cross-sectional study. The level of physical activity was measured over a mean period of 5.5 days with a triaxial accelerometer mounted on the thigh. Number of daily steps, number of daily short walking bouts of <10 s duration and number of daily transfers from sitting to standing position were recorded. Data were analysed using two sample
resultsPatients with KOA did not differ significantly from healthy participants regarding daily steps (+321,
conclusionPatients with KOA and KJR showed no significant reduction in number of daily step counts and transfers from sitting to standing position when compared with matched healthy controls. However, the number of short walking bouts was reduced in patients with KOA and by twice as much in patients with KJR. This indicates that KOA and treatment with KJR hardly affect health-related general activity but do affect specific physical activity behaviour potentially indicative of KOA or post-KJR functional limitations. THE TRANSLATIONAL POTENTIAL OF THIS ARTICLE: Activity monitoring with an accelerometer-based method gives insights into health-related general activity levels such as total daily steps and specific parameters such as short walking bouts, which may serve as an objective outcome measure in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.