Evidence map›Paper›PMID 30034938›Full record

ArticleAmerican journal of cancer research2018

Scinderin is a novel transcriptional target of BRMS1 involved in regulation of hepatocellular carcinoma cell apoptosis.

Xiaojing Qiao, Yiren Zhou, Wenjuan Xie, Yi Wang, Yicheng Zhang, Tian Tian, Jianming Dou, Xi Yang, Suqin Shen, Jianwei Hu and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Avicenna journal of medical biotechnology · 2026
    Article
  2. Scinderin promotes glioma cell migration and invasionWorld journal of clinical oncology · 2024
    Article
  3. Article
  4. Article
  5. Targeting AVIL, a New Cytoskeleton Regulator in Glioblastoma.International journal of molecular sciences · 2021
    Review
  6. Differential expression ofEXCLI journal · 2020
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Xiaojing QiaoSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Yiren ZhouSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Wenjuan XieSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Yi WangSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Yicheng ZhangSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Tian TianSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Jianming DouSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Xi YangSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Suqin ShenSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Jianwei HuEndoscopy Center and Department of General Surgery, Zhongshan Hospital of Fudan University Shanghai 200032, P. R. China.
Shouyi QiaoSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Yanhua WuSchool of Life Sciences, Fudan University Shanghai 200433, P. R. China.
Fudan University · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor metastasis suppressor factor BRMS1 can regulate the metastasis of breast cancer and other tumors. Here we report scinderin (SCIN) as a novel transcriptional target of BRMS1. SCIN protein belongs to the cytoskeletal gelsolin protein superfamily and its involvement in tumorigenesis remains largely illusive. An inverse correlation between the expression levels of BRMS1 and SCIN was observed in hepatocellular carcinoma (HCC) cells and tissues. On the molecular level, BRMS1 binds to

Indexed as

BRMS1cell apoptosishepatocellular carcinomascinderintranscriptional regulation

Identifiers

PMID30034938
PMCPMC6048394
OpenAlexW2998038076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.