Evidence map›Paper›PMID 30034798›Full record

ArticleAntimicrobial resistance and infection control2018

Outbreak report: a nosocomial outbreak of vancomycin resistant

Peter Kreidl, Astrid Mayr, Guido Hinterberger, Michael Berktold, Ludwig Knabl, Stefan Fuchs, Wilfried Posch, Stephan Eschertzhuber, Alois Obwegeser, Cornelia Lass-Flörl and 1 more

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
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  9. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022
    Article
  10. Current state of antimicrobial stewardship and organ transplantation in Spain.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Article
  11. Antibiogram Pattern and Virulence Trait Characterization ofJournal of laboratory physicians · 2022
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Epidemiology and risk factors of methicillin-resistantAntimicrobial resistance and infection control · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peter Kreidl1Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Schoepfstr. 41, 6020 Innsbruck, Austria.
Astrid Mayr1Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Schoepfstr. 41, 6020 Innsbruck, Austria.ORCID 0000-0002-8742-2817
Guido Hinterberger1Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Schoepfstr. 41, 6020 Innsbruck, Austria.
Michael Berktold1Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Schoepfstr. 41, 6020 Innsbruck, Austria.
Ludwig Knabl1Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Schoepfstr. 41, 6020 Innsbruck, Austria.
Stefan Fuchs1Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Schoepfstr. 41, 6020 Innsbruck, Austria.
Wilfried Posch1Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Schoepfstr. 41, 6020 Innsbruck, Austria.
Stephan Eschertzhuber2Department of Anesthesia and Critical Care, Centre of Operative Medicine, Medical University of Innsbruck, Anichstr. 35, 6020 Innsbruck, Austria.
Alois Obwegeser3Department of Neurosurgery, University Hospital of Innsbruck, Anichstr. 35, 6020 Innsbruck, Austria.
Cornelia Lass-Flörl1Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Schoepfstr. 41, 6020 Innsbruck, Austria.
Dorothea Orth-Höller1Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Schoepfstr. 41, 6020 Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vancomycin resistant Methods: We used retrospective patient and laboratory data including pulse field gel electrophoresis (PFGE) typing and virulence and resistance gene analysis. For comparison of medians the Mann-Whitney and for comparison of proportions the Fisher exact tests were used. Results: PFGE typing of VRE strains of an outbreak of 15 VRE cases in a solid transplant unit revealed that nine of the cases belonged to one identical pattern (A), which was only found twice in the environment. Eleven further positive environmental samples showed a different, but identical PFGE pattern E. Only one patient was infected with this environmental strain.Two of nine (22.2%) PFGE A, but nine of eleven (81.2%) PFGE E samples were positive for gelatinase E ( Conclusion: Routine disinfection was not able to stop the cluster, but after repeated enforcement of the infection prevention and control (IPC) bundle such as training, strict adherence to hand hygiene and surface disinfection no further cases were observed. We conclude that certain VRE strains predominate in the environment whereas others predominate in humans. Enforcement of the IPC bundle is essential for controlling VRE outbreaks and reducing further transmission.

Indexed as

Vancomycin ResistanceAdolescentAgedAnti-Bacterial AgentsAustriaChildCross InfectionElectrophoresis, Gel, Pulsed-FieldGram-Positive Bacterial InfectionsHumansMaleMiddle AgedOrgan TransplantationPhylogenyPostoperative ComplicationsRetrospective StudiesAnti-Bacterial AgentsVancomycinInfection controlOutbreakSolid organ transplant unitSurvival benefitVancomycin resistant enterococci

Identifiers

PMID30034798
PMCPMC6052578

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.