Evidence map›Paper›PMID 30034664›Full record

ArticleElectronic physician2018

Association between carotid intima-media thickness and ulcerative colitis: a systematic review and meta-analysis.

Ladan Goshayeshi, Ali Bahari, Farnaz Torabian, Kasra Molooghi, Ermia Musavi Mohammadi, Mehrdad Sahranavard, Hoda Hosseinzadeh Maleki, Zahra Sabzeh Noughabi, Benyamin Hoseini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Electronic physician, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ladan GoshayeshiDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali BahariDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Farnaz TorabianStudent Research Committee, Islamic Azad University, Mashhad Branch, Mashhad, Iran.
Kasra MolooghiStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ermia Musavi MohammadiStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mehrdad SahranavardStudent Research Committee, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Hoda Hosseinzadeh MalekiStudent Research Committee, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Zahra Sabzeh NoughabiClinical Research Development Unit (CRDU), 22 Bahman Hospital, Gonabad University of Medical Sciences, Gonabad, Iran.
Benyamin HoseiniDepartment of Health Information Technology, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Mashhad University of Medical Sciences · IRIslamic Azad University, Mashhad · IRNorth Khorasan University of Medical Sciences · IRUniversity of Neyshabur · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly detection of atherosclerosis is an essential means of decreasing cardiovascular events and its associated mortality. Systemic inflammatory diseases such as ulcerative colitis (UC), are thought to be a contributing factor to atherosclerosis due to the rise of inflammatory cytokines.

objectiveThe aim of this systematic review and meta-analysis was to assess the association between atherosclerosis and UC.

methodsThis systematic review and meta-analysis was performed in February 2017 with no date restrictions. PubMed, Cochrane Library and Embase were searched to discover all available observational studies on atherosclerosis among UC patients. The STROBE criteria were used to assess the quality of the included articles. Heterogeneity was assessed by the I-square statistic and publication bias with funnel plot and Egger's regression test. Overall summary mean difference was calculated as study effect size using random effect model. Comprehensive Meta-Analysis Software version 2.2 was used to perform analyses.

resultsA total of 5 articles met our eligibility criteria. We included a sum of 206 UC patients and 229 non-UC individuals in our review with a mean difference of c-IMT ranged from 0.03±0.0 to 0.16±0.03 mm, and a pooled mean difference of 0.127 mm (95% CI 0.058-0.195: I

conclusionOur findings showed significant differences in carotid intima-media thickness among UC and Non-UC groups, making c-IMT a viable choice as a predicting marker for atherosclerosis. Thus, we suggest that policy makers assess and consider its application in future protocols for the follow up and management of UC patients.

Indexed as

AtherosclerosisCardiovascular diseaseCarotid intima-media thicknessInflammatory bowel diseaseUlcerative colitis

Identifiers

PMID30034664
PMCPMC6049966
OpenAlexW2810375779

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.