Evidence map›Paper›PMID 30034616›Full record

ArticleACS medicinal chemistry letters2018

Using Tumor Explants for Imaging Mass Spectrometry Visualization of Unlabeled Peptides and Small Molecules.

Brian P David, Oleksii Dubrovskyi, Thomas E Speltz, Jeremy J Wolff, Jonna Frasor, Laura M Sanchez, Terry W Moore

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Real-Time Visualization of Endogenous HChemical & biomedical imaging · 2025
    Article
  2. A micropeptide regulates seed desiccation.Frontiers in plant science · 2025
    Article
  3. Review
  4. Making In Vitro Tumor Models Whole Again.Advanced healthcare materials · 2023
    Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Brian P DavidDepartment of Medicinal Chemistry and Pharmacognosy and UI Cancer Center, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, United States.
Oleksii DubrovskyiDepartment of Physiology and Biophysics and UI Cancer Center, University of Illinois at Chicago, 835 South Wolcott, Chicago, Illinois 60623, United States.
Thomas E SpeltzDepartment of Medicinal Chemistry and Pharmacognosy and UI Cancer Center, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, United States.
Jeremy J WolffBruker Daltonics, 40 Manning Road, Billerica, Massachusetts 01821, United States.
Jonna FrasorDepartment of Physiology and Biophysics and UI Cancer Center, University of Illinois at Chicago, 835 South Wolcott, Chicago, Illinois 60623, United States.
Laura M SanchezDepartment of Medicinal Chemistry and Pharmacognosy and UI Cancer Center, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, United States.
Terry W MooreDepartment of Medicinal Chemistry and Pharmacognosy and UI Cancer Center, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, United States.
University of Illinois Chicago · USBruker (United States) · US

Funding

Research Training in Natural Product Complementary and Integrative HealthT32AT007533 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Joanna E Burdette, JIMMY ORJALA · 2013 to 2026
$4.3M
NCCIH NIH HHS T32 AT007533
6 · The paper itself

Abstract

Matrix assisted laser desorption ionization time-of-flight (MALDI-TOF) imaging mass spectrometry has emerged as a powerful, label-free technique to visualize penetration of small molecules

Identifiers

PMID30034616
PMCPMC6047048
OpenAlexW2804478523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.