ArticlePakistan journal of medical sciences
Effect of Organophasphate poisoning among patients reporting at a tertiary healthcare facility of Sindh Pakistan.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- Epidemiology and mortality predictors of acute poisoning in a Tunisian Emergency Department: a two-year retrospective study.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2026Article
- Childhood and adolescent poisoning: a prospective analysis from the largest poison control centre.BMC pediatrics · 2026Article
- Evidence on Deliberate Self-Harm, Suicidal Ideation, and Suicides in Pakistan: A Scoping Review of Methods, Contributing Factors, and Associated Mental Disorders.Neuropsychobiology · 2026Review
- Clinical efficacy of the atropine and pralidoxime treatment combined with hemoperfusion in patients with acute organophosphate pesticide poisoning.Pakistan journal of medical sciences · 2025Article
- Suicides by pesticide ingestion in Pakistan and the impact of pesticide regulation.BMC public health · 2023Review
- A retrospective comparison of the burden of organophosphate poisoning to an Intensive Care Unit in Soweto over two separate periods.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2021Article
- Article
- Frequency of Acute Kidney Injury (AKI) among patients presenting with Organophosphate Poisoning at National Poison Control Centre, Karachi: A prospective cross-sectional survey.Pakistan journal of medical sciencesArticle
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the effect of organophosphate poisoning (OPP) among patients at tertiary healthcare, Pakistan.
methodsThis cohort study was conducted over a six-year period (January 2011 to December 2016) of OPP patients admitted to the intensive care unit of Peoples University of Medical & Health Sciences for Women SBA, Hospital Pakistan and their outcome was determined.
resultsTotal mortality was 17.39% (84 deaths in 483 patients, excluding those referred to Karachi). Out of these 84 deaths, 65 patients (13.46%) expired due to cardiorespiratory failure, 17 deaths (3.52%) followed due to complication of mechanical ventilation & ICU acquired infection and two deaths (0.41%) occurred due to renal failure. The major cause of poisoning was deliberate self-harm /suicidal intention (93.02%), with gender distribution of female (57.07%) and male (35.95%), followed by unintentional/accidental exposure (6.98%) in males. The intensive supportive treatment, precise and appropriate respiratory care, and adequate amount of atropine and pralidoxime doses are keys to reducing the OPP patient's mortality.
conclusionOrganophosphate poisoning (OPP) intoxication is common in female gender. The easy availability of these harmful compounds has resulted in increased mortality either by accidental exposure or most often by the deliberate suicidal attempt.
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