Evidence map›Paper›PMID 30034226›Full record

ReviewPatient preference and adherence2018

The new landscape of medication adherence improvement: where population health science meets precision medicine.

Leah L Zullig, Dan V Blalock, Samantha Dougherty, Rochelle Henderson, Carolyn C Ha, Megan M Oakes, Hayden B Bosworth

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Patient preference and adherence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  9. Review
  10. A Framework for Locating Prescribed Medication at Pharmacies.Integrated pharmacy research & practice · 2023
    Article
  11. Article
  12. The 2022 Ferno Award Address: CrEATE, an Efficient Crossover Evaluation of Addiction Treatment Efficacy.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leah L ZulligDurham Center for Health Services Research in Primary Care, Durham Veterans Affairs Health Care System, Durham, NC, USA, hayden.bosworth@duke.edu.
Dan V BlalockDurham Center for Health Services Research in Primary Care, Durham Veterans Affairs Health Care System, Durham, NC, USA, hayden.bosworth@duke.edu.
Samantha DoughertyPharmaceutical Research and Manufacturers of America, Washington, DC, USA.
Rochelle HendersonExpress Scripts Holding Company, St Louis, MO, USA.
Carolyn C HaPharmaceutical Research and Manufacturers of America, Washington, DC, USA.
Megan M OakesDepartment of Population Health Sciences, Duke University, Durham, NC, USA, hayden.bosworth@duke.edu.
Hayden B BosworthDurham Center for Health Services Research in Primary Care, Durham Veterans Affairs Health Care System, Durham, NC, USA, hayden.bosworth@duke.edu.

Funding

HSRD VA CDA 13-025HSRD VA IK2 HX001345HSRD VA RCS 08-027
6 · The paper itself

Abstract

Despite the known health and economic benefits of medications, nonadherence remains a significant, yet entirely preventable public health burden. Over decades, there have been numerous research studies evaluating health interventions and policy efforts aimed at improving adherence, yet no universal or consistently high impact solutions have been identified. At present, new challenges and opportunities in policy and the movement toward value-based care should foster an environment that appreciates adherence as a mechanism to improve health outcomes and control costs (eg, fewer hospitalizations, reduced health care utilization). Our objective was to provide a commentary on recent changes in the landscape of research and health policy directed toward improving adherence and an actionable agenda to achieve system level savings and improved health by harnessing the benefits of medications. Specifically, we address the complementary perspectives of precision medicine and population health management; integrating data sources to develop innovative measurement of adherence and target adherence interventions; and behavioral economics to determine appropriate incentives.

Indexed as

adherencepolicypopulation healthprecision medicine

Identifiers

PMID30034226
PMCPMC6049050

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.