Evidence map›Paper›PMID 30034202›Full record

ArticlePolymers for advanced technologies2016

Tungsten-loaded SMP foam nanocomposites with inherent radiopacity and tunable thermo-mechanical properties.

Sayyeda M Hasan, Garrett Harmon, Fang Zhou, Jeffery E Raymond, Tiffany P Gustafson, Thomas S Wilson, Duncan J Maitland

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers for advanced technologies, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sayyeda M HasanDepartment of Biomedical Engineering, 5045 Emerging Technologies Building, Texas A&M University, 3120 TAMU, College Station, TX, 77843-3120, USA.
Garrett HarmonDepartment of Biomedical Engineering, 5045 Emerging Technologies Building, Texas A&M University, 3120 TAMU, College Station, TX, 77843-3120, USA.
Fang ZhouCharacterization Facility, College of Science and Engineering, 1-234 Nils Hasselmo Hall, 312, University of Minnesota, Church Street S. E., Minneapolis, MN, 55455, USA.
Jeffery E RaymondTexas A&M University, Laboratory for Synthetic-Biologic Interactions, Department of Chemistry, 1031 Chemistry Complex, 3012 TAMU, College Station, TX, 77842, USA.
Tiffany P GustafsonTexas A&M University, Laboratory for Synthetic-Biologic Interactions, Department of Chemistry, 1031 Chemistry Complex, 3012 TAMU, College Station, TX, 77842, USA.
Thomas S WilsonLawrence Livermore National Laboratory, 7000 East Ave., Livermore, CA, 94550, USA.
Duncan J MaitlandDepartment of Biomedical Engineering, 5045 Emerging Technologies Building, Texas A&M University, 3120 TAMU, College Station, TX, 77843-3120, USA.

Funding

Shape Memory Polymer Devices for Treating StrokeR01EB000462 · NIBIB · UNIVERSITY OF CALIF-LAWRNC LVRMR NAT LAB · PI MAITLAND, DUNCAN J · 2002 to 2012
$12.5M
NIBIB NIH HHS R01 EB000462
6 · The paper itself

Abstract

Shape memory polymer (SMP) foams have been developed for use in neurovascular occlusion applications. These materials are predominantly polyurethanes that are known for their biocompatibility and tunable properties. However, these polymers inherently lack X-ray visibility, which is a significant challenge for their use as implantable materials. Herein, low density, highly porous shape memory polyurethane foams were developed with tungsten nanoparticles dispersed into the foam matrix, at increasing concentrations, to serve as a radiopaque agent. Utilizing X-ray fluoroscopy sufficient visibility of the foams at small geometries was observed. Thermal characterization of the foams indicated altered thermal response and delayed foam actuation with increasing nanoparticle loading (because of restricted network mobility). Mechanical testing indicated decreased toughness and strength for higher loading because of disruption of the SMP matrix. Overall, filler addition imparted x-ray visibility to the SMP foams and allowed for tuned control of the transition temperature and actuation kinetics for the material.

Indexed as

aneurysmdispersionglass transition temperaturenanocompositeradiopacity

Identifiers

PMID30034202
PMCPMC6052881

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.