ArticleVeterinary world2018
The effectiveness of platelet-rich plasma on the skin wound healing process: A comparative experimental study in sheep.
Article in Veterinary world, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 26 citations in OpenAlex.
- Conventional Versus Regenerative Methods for Wound Healing: A Comparative Experimental Study on a Sheep Model.Medicina (Kaunas, Lithuania) · 2024Article
- Mutable Collagenous Tissue Isolated from Echinoderms Leads to the Production of a Dermal Template That Is Biocompatible and Effective for Wound Healing in Rats.Marine drugs · 2023Article
- Assessment of the quality of the healing process in experimentally induced skin lesions treated with autologous platelet concentrate associated or unassociated with allogeneic mesenchymal stem cells: preliminary results in a large animal model.Frontiers in veterinary science · 2023Article
- Wound healing effects and antibacterial properties of heterologous platelet-rich plasma onJournal of advanced veterinary and animal research · 2022Article
- The Sheep as a Large Animal Model for the Investigation and Treatment of Human Disorders.Biology · 2022Review
- Comparative study of the therapeutic efficacy of autologous platelet-rich plasma and honey in healing skin wounds in sheep.Veterinary world · 2021Article
- Small Ruminants and Its Use in Regenerative Medicine: Recent Works and Future Perspectives.Biology · 2021Review
- Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs.Frontiers in veterinary science · 2020Article
- The Composition of Hyperacute Serum and Platelet-Rich Plasma Is Markedly Different despite the Similar Production Method.International journal of molecular sciences · 2019Article
- Biological and Mechanical Properties of Platelet-Rich Fibrin Membranes after Thermal Manipulation and Preparation in a Single-Syringe Closed System.International journal of molecular sciences · 2018Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe therapeutic evaluation of the biological effect of platelet-rich plasma (PRP) used as a surgical adjunct to maintain the inflammatory process and to potentiate tissue healing, make the subject of recent research in regenerative medicine. This study was designed to evaluate the healing activity of PRP by its topical application on the skin experimentally injured in a sheep model. MATERIALS AND
methodsThe study was conducted on 9 adult and clinically healthy males sheep. PRP was obtained by a protocol of double centrifugation of whole blood from each animal. After sterile skin preparation, full-thickness excisional wounds (20 mm x 20 mm) were created on the back of each animal. The animals were randomly divided into three equal groups of three sheep for each. In Group I, the wounds were treated with PRP, in Group II; wounds were treated with Asiaticoside; in Group III, wounds were treated with saline solution. The different treatments were administered topically every 3 days. Morphometric measurements of the contraction surface of the wounds and histopathological biopsies were carried out at the 3
resultsThe results of the morphometric data obtained revealed that it was significant differences recorded at the 7
conclusionWe concluded that topical administration of PRP obtained by double centrifugation protocol could potentially improve the skin healing process in sheep.
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Registered trials
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