Evidence map›Paper›PMID 30033984›Full record

ArticleThe Journal of reproduction and development2018

Localization of SOX2-positive stem/progenitor cells in the anterior lobe of the common marmoset (Callithrix jacchus) pituitary.

Saishu Yoshida, Ken Fujiwara, Takashi Inoue, Erika Sasaki, Yoshie Kametani, Susumu Takekoshi, Naoko Inoshita, Takako Kato, Yukio Kato

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of reproduction and development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Saishu YoshidaDivision of Life Science, Graduate School of Agriculture, Meiji University, Kanagawa 214-8571, Japan.
Ken FujiwaraDivision of Histology and Cell Biology, Department of Anatomy, Jichii Medical University School of Medicine, Tochigi, 329-0498, Japan.
Takashi InoueCentral Institute for Experimental Animals, Kanagawa 210-0821, Japan.
Erika SasakiCentral Institute for Experimental Animals, Kanagawa 210-0821, Japan.
Yoshie KametaniDepartment of Molecular Life Science, Division of Basic Medical Science, Tokai University School of Medicine, Kanagawa 259-1193, Japan.
Susumu TakekoshiDepartment of Cell Biology, Division of Host Defense Mechanism, Tokai University School of Medicine, Kanagawa 259-1193, Japan.
Naoko InoshitaDepartment of Pathology, Toranomon Hospital, Tokyo 105-8470, Japan.
Takako KatoOrganization for the Strategic Coordination of Research and Intellectual Property, Meiji University, Kanagawa 214-8571, Japan.
Yukio KatoDivision of Life Science, Graduate School of Agriculture, Meiji University, Kanagawa 214-8571, Japan.
Meiji University · JPCentral Institute for Experimental Animals · JPTokai University · JPJichi Medical University · JPToranomon Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies on mouse and rat pituitaries reported that Sox2-expressing cells play roles as stem/progenitor cells in the adult pituitary gland. The presence of cells with stem cell-like properties in the pituitary adenoma and SOX2-positive cells has been demonstrated in the human pituitary. However, considering the difficulty in fully examining the stem/progenitor cell properties in the human pituitary, in the present study, we analyzed the SOX2-positive cells in the pituitary of the adult common marmoset (Callithrix jacchus), which is used as a non-human primate model. Immunohistochemistry demonstrated that localization pattern of SOX2-positive cells in the common marmoset pituitary was similar to that observed in the rodent pituitary, i.e., in the two types of niches (marginal cell layer and parenchymal-niche) and as scattered single cells in the parenchyma of the anterior lobe. Furthermore, most of the SOX2-positive cells express S100 and were located in the center or interior of LAMININ-positive micro-lobular structures. Collectively, the present study reveals properties of SOX2-positive cells in the common marmoset pituitary and suggests that the common marmoset proves to be a useful tool for analyzing pituitary stem/progenitor cells in a non-human primate model.

Indexed as

AnimalsCallithrixCell DifferentiationFemaleImmunohistochemistryLamininMalePituitary Gland, AnteriorRatsRats, WistarSOXB1 Transcription FactorsStem Cell NicheStem CellsTemperatureLamininSOXB1 Transcription FactorsCommon marmoset pituitaryMicro-lobular structureS100Stem/progenitor cells

Identifiers

PMID30033984
PMCPMC6189570
OpenAlexW2884075873

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.