Evidence map›Paper›PMID 30033869›Full record

ReviewCurrent drug delivery2018

A Summary of Electrospun Nanofibers as Drug Delivery System: Drugs Loaded and Biopolymers Used as Matrices.

Erick José Torres-Martinez, José Manuel Cornejo Bravo, Aracely Serrano Medina, Graciela Lizeth Pérez González, Luis Jesús Villarreal Gómez

Abstract readReview
In one paragraph

Review in Current drug delivery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Tailoring the Release of Paclitaxel from Electrospun Nonwovens.International journal of molecular sciences · 2025
    Article
  10. Article
  11. Article
  12. Chitosan-Based Nanoencapsulation of Mānuka Oil for Periodontal Treatment.International journal of molecular sciences · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erick José Torres-MartinezUniversidad Autonoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana Baja California C.P. 22390, Mexico.
José Manuel Cornejo BravoUniversidad Autonoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana Baja California C.P. 22390, Mexico.
Aracely Serrano MedinaUniversidad Autonoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana Baja California C.P. 22390, Mexico.
Graciela Lizeth Pérez GonzálezUniversidad Autonoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana Baja California C.P. 22390, Mexico.
Luis Jesús Villarreal GómezUniversidad Autonoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana Baja California C.P. 22390, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, electrospun polymeric nanofibers have proven to be an interesting strategy for drug delivery systems application. The high surface-to-volume ratio of the fibers can improve some processes, such as cell binding and proliferation, drug loading, and mass transfer processes. One of the most important and studied areas of electrospinning is in the drug delivery field, for the controlled release of active substances ranging from antibiotics and anticancer agents to macromolecules such as proteins and DNA. The advantage of this method is that a wide variety of low solubility drugs can be loaded into the fibers to improve their bioavailability or to attain controlled release. This review presents an overview of the reported drugs loaded into polymeric nanofibers, to be used as drug delivery systems. For instance, it presents the reports on drugs with different bioactivities such as antiinflammatory, anti-microbial, anticancer, cardiovascular, anti-histamine, gastrointestinal, palliative and contraceptive drugs, etc. It also analyzes the electrospinning techniques used in each system, as well as the polymers used as matrices for the preparation of the nanofibers; unfolding the advantages of electrospun polymeric nanofibers over other drug delivery systems. This review intends to enlist and summarize the reported literature concerning this topic. In addition, it proposes future research in the field.

Indexed as

Drug Delivery SystemsAnimalsAnti-Bacterial AgentsAntineoplastic AgentsBiopolymersHumansNanofibersAnti-Bacterial AgentsAntineoplastic AgentsBiopolymersBiopolymerscontrolled releasedrug releaseelectrospinningfast releasenanofibers.

Identifiers

PMID30033869
PMCPMC6376322

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.