ArticleAutophagy2018
Anti- and pro-microbial roles of autophagy in plant-bacteria interactions.
Article in Autophagy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Vacuolar sorting receptors coordinate lytic vacuolar and autophagic transport for plant effector-triggered immunity.Nature plants · 2025Article
- An asymptomatic geminivirus activates autophagy and enhances plant defenses against diverse pathogens.Stress biology · 2024Article
- Clathrin light chains negatively regulate plant immunity by hijacking the autophagy pathway.Plant communications · 2024Article
- The Role of Plant Ubiquitin-like Modifiers in the Formation of Salt Stress Tolerance.Plants (Basel, Switzerland) · 2024Review
- NBR1: The archetypal selective autophagy receptor.The Journal of cell biology · 2022Review
- Selective autophagy: adding precision in plant immunity.Essays in biochemistry · 2022Article
- A bacterial effector counteracts host autophagy by promoting degradation of an autophagy component.The EMBO journal · 2022Article
- Cargo Recognition and Function of Selective Autophagy Receptors in Plants.International journal of molecular sciences · 2021Review
- Review
- Emerging Roles of the Selective Autophagy in Plant Immunity and Stress Tolerance.International journal of molecular sciences · 2020Review
- Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Macroautophagy/autophagy and the ubiquitin-proteasome system (UPS) are major proteolytic pathways that are increasingly recognized as battlegrounds during host-microbe interactions in eukaryotes. In plants, the UPS has emerged as central component of innate immunity and is manipulated by bacterial pathogens to enhance virulence. Autophagy has been ascribed a similar importance for anti-bacterial immunity in animals, but the contribution of autophagy to host-bacteria interactions remained elusive in plants. Here, we present and discuss our recent findings that revealed anti- and pro-bacterial roles of autophagy pathways during bacterial infection in the model plant Arabidopsis thaliana. We discovered that selective autophagy mediated by the autophagy cargo receptor AT4G24690/NBR1 limits growth of Pseudomonas syringae pv. tomato DC3000 (Pst) by suppressing the establishment of an aqueous extracellular space ('water-soaking'). In turn, Pseudomonas employs the effector protein HopM1 to activate autophagy and proteasome degradation ('proteaphagy'), thereby enhancing its pathogenicity. Thus, our study demonstrates that distinct selective autophagy pathways contribute to host immunity and bacterial pathogenesis during Pst infection and provide evidence for an intimate crosstalk between the proteasome and autophagy system in plant-bacterial interactions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.