Evidence map›Paper›PMID 30033139›Full record

ArticleCytokine2019

CD8

Sarah M Clark, Chang Song, Xin Li, Achsah D Keegan, Leonardo H Tonelli

Abstract read
In one paragraph

Article in Cytokine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Combined Supplementation ofInternational journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah M ClarkLaboratory of Behavioral Neuroimmunology, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA; Research and Development Service, Department of Veterans Affairs, VA Maryland Health Care System, Baltimore, MD, USA.
Chang SongLaboratory of Behavioral Neuroimmunology, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Xin LiLaboratory of Behavioral Neuroimmunology, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Achsah D KeeganCenter for Vascular and Inflammatory Diseases, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA; Research and Development Service, Department of Veterans Affairs, VA Maryland Health Care System, Baltimore, MD, USA.
Leonardo H TonelliLaboratory of Behavioral Neuroimmunology, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA; Research and Development Service, Department of Veterans Affairs, VA Maryland Health Care System, Baltimore, MD, USA. Electronic address: ltonelli@som.umaryland.edu.
University of Maryland, Baltimore · US

Funding

Neuroimmune Mechanisms of Risk and Resilience to Maladaptive Responses to StressR01MH097676 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI TONELLI, LEONARDO H · 2011 to 2014
$1.5M
Regulation of Macrophage Activation by House Dust MiteI01BX001850 · VA · BALTIMORE VA MEDICAL CENTER · PI KEEGAN, ACHSAH D. · 2013 to 2022
–
Targeting the inflammatory response to treat post-traumatic anxiety and depression.I01BX003631 · VA · BALTIMORE VA MEDICAL CENTER · PI GOULD, TODD D · 2017 to 2021
–
BLRD VA I01 BX001850BLRD VA I01 BX003631NIMH NIH HHS R01 MH097676
6 · The paper itself

Abstract

Psychological stress is known to have profound effects on immune function and to promote inflammatory conditions. Elevated circulating levels of cytokines associated with stress are known to increase the risk to several diseases, but little is known about this mechanism. This study assessed the role of T cells on cytokine levels after exposure to stress in the learned helplessness paradigm. Adoptive transfer of CD4

Indexed as

Lymphocyte ActivationAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCytokinesDNA-Binding ProteinsHyaluronan ReceptorsL-SelectinMiceMice, KnockoutStress, PsychologicalCd44 protein, mouseCytokinesDNA-Binding ProteinsHyaluronan ReceptorsL-SelectinRag2 protein, mouseBrainCorticosteroneInterleukinsStressTumor necrosis factor alpha

Identifiers

PMID30033139
PMCPMC6289779
OpenAlexW2883527219

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.