ArticleAnalytical and bioanalytical chemistry2018
Subcellular mapping of living cells via synchrotron microFTIR and ZnS hemispheres.
Article in Analytical and bioanalytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Rapid single-live-cell scanningMethodsX · 2026Article
- Morphological and Chemical Changes in the Trophozoites and Cysts of Acanthamoeba Castellanii Induced by Camellia Sinensis Extracts.Acta parasitologica · 2025Article
- Modeling the Thermoelastic Sample Response for Subdiffraction Infrared Spectroscopic Imaging.Chemical & biomedical imaging · 2024Article
- Recent advances in single-cell subcellular sampling.Chemical communications (Cambridge, England) · 2023Review
- Metasurface-enhanced infrared spectroscopy in multiwell format for real-time assaying of live cells.Lab on a chip · 2023Article
- Synchrotron Infrared Microspectroscopy for Stem Cell Research.International journal of molecular sciences · 2022Review
- Article
- Infrared-spectroscopic, dynamic near-field microscopy of living cells and nanoparticles in water.Scientific reports · 2021Article
- X-ray-Based Techniques to Study the Nano-Bio Interface.ACS nano · 2021Article
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5 authors.
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Abstract
FTIR imaging is a label-free, non-destructive method valuably exploited in the study of the biological process in living cells. However, the long wavelength/low spatial resolution and the strong absorbance of water are still key constrains in the application of IR microscopy ex vivo. In this work, a new retrofit approach based on the use of ZnS hemispheres is introduced to significantly improve the spatial resolution on live cell FTIR imaging. By means of two high refractive index domes sandwiching the sample, a lateral resolution close to 2.2 μm at 6 μm wavelength has been achieved, i.e. below the theoretical diffraction limit in air and more than twice the improvement (to ~λ/2.7) from our previous attempt using CaF
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