Evidence map›Paper›PMID 30031874›Full record

Trial reportJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2018

Correlation of monocular grating acuity at age 12 months with recognition acuity at age 4.5 years: findings from the Infant Aphakia Treatment Study.

E Eugenie Hartmann, Carolyn Drews-Botsch, Lindreth G DuBois, George Cotsonis, Scott R Lambert, Infant Aphakia Treatment Study Group

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00212134 (Infant Aphakia Treatment Study), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00212134 nacompletednot on this map

Infant Aphakia Treatment Study (IATS)

TypeinterventionalSponsorStanford UniversityRan2004 to 2020Enrolled114ConditionsCongenital CataractArmsContact lens correction of aphakia, Intraocular lens implantation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

E Eugenie HartmannDepartment of Vision Sciences, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: ghartm3@emory.edu.
Carolyn Drews-BotschEpidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Lindreth G DuBoisDepartment of Ophthalmology, School of Medicine, Emory University, Atlanta, Georgia.
George CotsonisEpidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Scott R LambertDepartment of Ophthalmology, Stanford University, Stanford, California.
Infant Aphakia Treatment Study Group
Emory University · USStanford University · USUniversity of Alabama at Birmingham · US

Funding

P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI BOATRIGHT, JEFFREY H · 1986 to 2025
$15.3M
Infant Aphakia Treatment StudyU10EY013272 · NEI · EMORY UNIVERSITY · PI LAMBERT, SCOTT R · 2004 to 2014
$8.1M
Coordinating Center for Infant Aphakia Treatment Study (IATS)U10EY013287 · NEI · EMORY UNIVERSITY · PI LONG, QI · 2004 to 2014
$5.8M
Infant Aphakia Treatment Study-Clinical CentersUG1EY025553 · NEI · EMORY UNIVERSITY · PI DREWS-BOTSCH, CAROLYN DAWSON · 2015 to 2018
$933k
Coordinating Center for Infant Aphakia Treatment Study (IATS)UG1EY013287 · NEI · EMORY UNIVERSITY · PI NIZAM, AZHAR · 2015 to 2018
$917k
Infant Aphakia Treatment Study-Chairman's GrantUG1EY013272 · NEI · STANFORD UNIVERSITY · PI LAMBERT, SCOTT R · 2015 to 2018
$639k
NEI NIH HHS P30 EY006360NEI NIH HHS U10 EY013272NEI NIH HHS U10 EY013287NEI NIH HHS UG1 EY013272NEI NIH HHS UG1 EY013287NEI NIH HHS UG1 EY025553
6 · The paper itself

Abstract

purposeTo determine whether grating acuity at age 12 months can be used to predict recognition acuity at age 4.5 years in children treated for unilateral congenital cataract enrolled in the Infant Aphakia Treatment Study (IATS).

methodsTraveling testers assessed monocular grating acuity at 12 months of age (Teller Acuity Card Test [TACT]) and recognition acuity at 4.5 years of age (Amblyopia Treatment Study Electronic Visual Acuity Testing, HOTV) in children treated for visually significant monocular cataract in the IATS. Spearman rank correlation was used to evaluate the relationship between visual acuities at the two ages in the treated eyes.

resultsVisual acuity data at both ages were available for 109 of 114 children (96%). Grating acuity at 12 months of age and recognition acuity at 4.5 years of age were significantly correlated for the treated eyes (r

conclusionsA single grating acuity assessment at age 12 months predicts recognition acuity in a child treated for unilateral congenital cataract in only two-thirds of cases. Clinicians should consider other factors, such as patching compliance and age at surgery, when using an early grating acuity assessment to modify treatment.

Indexed as

Aphakia, PostcataractChild, PreschoolFemaleHumansInfantMalePredictive Value of TestsRecognition, PsychologyVision, MonocularVisual Acuity

Identifiers

PMID30031874
PMCPMC7872073
OpenAlexW2884564386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.