Evidence map›Paper›PMID 30031838›Full record

ArticleExperimental gerontology2018

Maximal strength training increases muscle force generating capacity and the anaerobic ATP synthesis flux without altering the cost of contraction in elderly.

Ole Kristian Berg, Oh Sung Kwon, Thomas J Hureau, Heather L Clifton, Taylor Thurston, Yann Le Fur, Eun-Kee Jeong, Markus Amann, Russel S Richardson, Joel D Trinity and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Experimental gerontology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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  15. Skeletal Muscle Mitochondrial Adaptations to Maximal Strength Training in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Ole Kristian BergFaculty of Health and Social Sciences, Molde University College, Molde, Norway. Electronic address: olbe@himolde.no.
Oh Sung KwonDepartment of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA; Geriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center, Salt Lake City, UT, USA.
Thomas J HureauDepartment of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA; Geriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center, Salt Lake City, UT, USA.
Heather L CliftonDepartment of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA; Geriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center, Salt Lake City, UT, USA.
Taylor ThurstonDepartment of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA; Geriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center, Salt Lake City, UT, USA; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.
Yann Le FurCRMBM, Aix-Marseille Universite, CNRS 7339, Marseille, France.
Eun-Kee JeongDepartment of Radiology, Utah Center for Advanced Imaging Research, University of Utah, Salt Lake City, UT, USA.
Markus AmannGeriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center, Salt Lake City, UT, USA; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA; Department of Anesthesiology, University of Utah, Salt Lake City, UT, USA.
Russel S RichardsonDepartment of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA; Geriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center, Salt Lake City, UT, USA; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.
Joel D TrinityDepartment of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA; Geriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center, Salt Lake City, UT, USA; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.
Eivind WangFaculty of Health and Social Sciences, Molde University College, Molde, Norway; Department of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA; Department of Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Department of Research and Development, St. Olav's University Hospital, Trondheim, Norway.
Gwenael LayecDepartment of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA; Geriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center, Salt Lake City, UT, USA; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.
University of Utah · USMolde University College · NOCentre National de la Recherche Scientifique · FR

Funding

Role of Sensory Neurons in Human Cardiovascular DiseaseR01HL116579 · NHLBI · UNIVERSITY OF UTAH · PI AMANN, MARKUS · 2013 to 2021
$3.4M
Nitric oxide coupling and BH4 availability roles in muscle dysfunction with COPDR00HL125756 · NHLBI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI LAYEC, GWENAEL · 2018 to 2020
$738k
Nitric oxide coupling and BH4 availability roles in muscle dysfunction with COPDK99HL125756 · NHLBI · UNIVERSITY OF UTAH · PI LAYEC, GWENAEL · 2015 to 2016
$300k
Understanding the Exercise-Hypertension Paradox: Implication for RehabilitationIK2RX001215 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI TRINITY, JOEL DOUGLAS · 2014 to 2018
–
NHLBI NIH HHS K99 HL125756NHLBI NIH HHS R00 HL125756NHLBI NIH HHS R01 HL116579RRD VA IK2 RX001215
6 · The paper itself

Abstract

Aging is associated with a progressive decline in skeletal muscle function, then leading to impaired exercise tolerance. Maximal strength training (MST) appears to be a practical and effective intervention to increase both exercise capacity and efficiency. However, the underlying physiological mechanisms responsible for these functional improvements are still unclear. Accordingly, the purpose of this study was to examine the intramuscular and metabolic adaptations induced by 8 weeks of knee-extension MST in the quadriceps of 10 older individuals (75 ± 9 yrs) by employing a combination of molecular, magnetic resonance

Indexed as

ExerciseIsometric ContractionAdaptation, PhysiologicalAdenosine TriphosphateAgedAged, 80 and overAgingEnergy MetabolismExercise ToleranceFemaleGlycolysisHumansKneeMaleMuscle StrengthQuadriceps MuscleAdenosine Triphosphate(31)P-MRSAgingATP cost of contractionEnergetic propertiesGlycolysisStrength training

Identifiers

PMID30031838
PMCPMC6309209
OpenAlexW2883226876

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.