Evidence map›Paper›PMID 30031815›Full record

ArticleJournal of molecular and cellular cardiology2018

Mitochondrial complex I in the post-ischemic heart: reperfusion-mediated oxidative injury and protein cysteine sulfonation.

Patrick T Kang, Chwen-Lih Chen, Paul Lin, Liwen Zhang, Jay L Zweier, Yeong-Renn Chen

Abstract read
In one paragraph

Article in Journal of molecular and cellular cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Rescuing Ischemic Brain Injury by Rewiring Mitochondrial Electron Flow.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. RBM15 Protects From Myocardial Infarction by Stabilizing NAE1.JACC. Basic to translational science · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. A Novel 5-Chloro-Molecules (Basel, Switzerland) · 2023
    Article
  11. Potential Roles of mtDNA Mutations in PCOS-IR: A Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Review
  12. Article
  13. Review
  14. Mitochondrial redox regulation and myocardial ischemia-reperfusion injury.American journal of physiology. Cell physiology · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Patrick T KangDepartment of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, OH 44272, United States.
Chwen-Lih ChenDepartment of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, OH 44272, United States.
Paul LinDepartment of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, OH 44272, United States.
Liwen ZhangCampus Chemical Instrument Center, Proteomics and Mass Spectrometry Facility, The Ohio State University, Columbus, OH 43210, United States.
Jay L ZweierDavis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, United States.
Yeong-Renn ChenDepartment of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, OH 44272, United States. Electronic address: ychen1@neomed.edu.
Northeast Ohio Medical University · USLung Institute · USThe Ohio State University · US

Funding

Role of Cytoglobin in the Regulation of Vascular ToneR01HL131941 · NHLBI · OHIO STATE UNIVERSITY · PI JAY Louis ZWEIER · 2017 to 2026
$5.7M
Myocardial Injury Mitochondria/ Oxygen Free Radical(s)R01HL083237 · NHLBI · OHIO STATE UNIVERSITY · PI CHEN, YEONG-RENN · 2006 to 2017
$3.8M
Mechanisms of Nicotine Inhalation-Induced Cardiovascular DiseaseR01HL135648 · NHLBI · OHIO STATE UNIVERSITY · PI ZWEIER, JAY LOUIS · 2017 to 2021
$2.6M
NHLBI NIH HHS R01 HL083237NHLBI NIH HHS R01 HL131941NHLBI NIH HHS R01 HL135648
6 · The paper itself

Abstract

A serious consequence of ischemia-reperfusion injury (I/R) is oxidative damage leading to mitochondrial dysfunction. Such I/R-induced mitochondrial dysfunction is observed as impaired state 3 respiration and overproduction of O

Indexed as

AnimalsCysteineElectron Transport Complex IHumansMiceMitochondriaMitochondria, HeartMyocardial InfarctionMyocardial Reperfusion InjuryOxidative StressRatsTandem Mass SpectrometryCysteinecysteine sulfonateElectron Transport Complex IComplex IMitochondrial dysfunctionMyocardial ischemia and reperfusionProtein cysteine sulfonationProtein structure

Identifiers

PMID30031815
PMCPMC6103816
OpenAlexW2883785633

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.