ArticleInternational journal of radiation oncology, biology, physics2018
Dose Prediction Model for Duodenum Sparing With a Biodegradable Hydrogel Spacer for Pancreatic Cancer Radiation Therapy.
Article in International journal of radiation oncology, biology, physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Evaluating Curvature-Induced Variation in Deep Learning-Based Beamforming for Flexible Transducers in Ultrasound-Guided Radiation Therapy.Bioengineering (Basel, Switzerland) · 2026Article
- Hydrogel adhesives for upper gastrointestinal wound healing.Theranostics · 2026Review
- Recent advances in hydrogel-based delivery systems for the treatment of pancreatic cancer.Materials today. Bio · 2025Review
- Article
- Ultrasound Imaging with Flexible Array Transducer for Pancreatic Cancer Radiation Therapy.Cancers · 2023Article
- DAART: a deep learning platform for deeply accelerated adaptive radiation therapy for lung cancer.Frontiers in oncology · 2023Article
- Systematic study of the iodinated rectal hydrogel spacer material discrepancy on accuracy of proton dosimetry.Journal of applied clinical medical physics · 2022Article
- Automatic treatment planning for cervical cancer radiation therapy using direct three-dimensional patient anatomy match.Journal of applied clinical medical physics · 2022Article
- Demonstrating the benefits of corrective intraoperative feedback in improving the quality of duodenal hydrogel spacer placement.Medical physics · 2022Article
- A phantom-based analysis for tracking intra-fraction pancreatic tumor motion by ultrasound imaging during radiation therapy.Frontiers in oncology · 2022Article
- Finite Element-Based Personalized Simulation of Duodenal Hydrogel Spacer: Spacer Location Dependent Duodenal Sparing and a Decision Support System for Spacer-Enabled Pancreatic Cancer Radiation Therapy.Frontiers in oncology · 2022Article
- Employing hydrogels in tissue engineering approaches to boost conventional cancer-based research and therapies.RSC advances · 2021Review
- The Feasibility of Haar Feature-Based Endoscopic Ultrasound Probe Tracking for Implanting Hydrogel Spacer in Radiation Therapy for Pancreatic Cancer.Frontiers in oncology · 2021Article
- The use of hyperbaric oxygen to treat actinic rectal fistula after SpaceOAR use and radiotherapy for prostate cancer: a case report.BMC urology · 2020Article
- Clinical outcomes and prognostic factors of stereotactic body radiation therapy combined with gemcitabine plus capecitabine for locally advanced unresectable pancreatic cancer.Journal of cancer research and clinical oncology · 2020Article
- A Beam-Specific Optimization Target Volume for Stereotactic Proton Pencil Beam Scanning Therapy for Locally Advanced Pancreatic Cancer.Advances in radiation oncologyArticle
- Evaluation of Auto-Planning for Left-Side Breast Cancer After Breast-Conserving Surgery Based on Geometrical Relationship.Technology in cancer research & treatmentArticle
- Evaluation of a Novel Absorbable Radiopaque Hydrogel in Patients Undergoing Image Guided Radiation Therapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma.Practical radiation oncologyArticle
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Authors and funding
13 authors.
Funding
Abstract
purposeWe previously have shown the feasibility of duodenum sparing using a biodegradable hydrogel spacer in pancreatic cancer radiation therapy. In this study, we propose an overlap volume histogram (OVH) prediction model to select patients who might benefit from hydrogel placement and to predict the hydrogel spacing required to achieve clinical constraints. METHODS AND MATERIALS: OVH metrics for the duodenum were collected from the stereotactic body radiation therapy plans of 232 patients with unresectable pancreatic cancer (33 Gy in 5 fractions). OVH metrics L
resultsLinear regression analysis showed a significant correlation between L
conclusionOur model may predict which patients require placement of a hydrogel spacer before stereotactic body radiation therapy to meet predefined dose constraints. Furthermore, by predicting the required target hydrogel thickness, the spacer injection can be better guided to improve efficacy.
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