Evidence map›Paper›PMID 30031057›Full record

ReviewJournal of biomedical informatics2018

Relief-based feature selection: Introduction and review.

Ryan J Urbanowicz, Melissa Meeker, William La Cava, Randal S Olson, Jason H Moore

Abstract readReview
In one paragraph

Review in Journal of biomedical informatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 226 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
226citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

226 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Computational Pipeline in Neuroradiomics.Methods in molecular biology (Clifton, N.J.) · 2026
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166 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryan J UrbanowiczInstitute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: ryanurb@upenn.edu.
Melissa MeekerUrsinus College, Collegeville, PA 19426, USA. Electronic address: memeeker@ursinus.edu.
William La CavaInstitute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: lacava@upenn.edu.
Randal S OlsonInstitute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: olsonran@upenn.edu.
Jason H MooreInstitute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: jhmoore@upenn.edu.

Funding

Human Pancreas Analysis Program for Type 1 Diabetes - HPAP-T1DU01DK112217 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MARK A. ATKINSON, KLAUS H KAESTNER · 2021 to 2026
$46.8M
Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Rebecca A Simmons · 2006 to 2026
$35.3M
Rare Diseases Data Management and Coordinating CenterU01TR001263 · NCATS · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2014 to 2018
$28.1M
Penn integrated Human Pancreas procurement and Analysis ProgramUC4DK112217 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI BETTS, MICHAEL R, FELDMAN, MICHAEL D · 2016 to 2020
$17.8M
Bioinformatics Strategies for Genome-Wide Association StudiesR01LM010098 · NLM · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H., WILLIAMS, SCOTT MATTHEW · 2009 to 2023
$5.1M
Machine Learning Prediction of Cancer SusceptibilityR01LM009012 · NLM · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H. · 2006 to 2014
$3.3M
Approaches to Genetic Heterogeneity of Obstructive Sleep ApneaR01HL134015 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PACK, ALLAN I, ROBISHAW, JANET D · 2016 to 2019
$3.2M
Biomedical Computing and Informatics Strategies for Infectious Disease ResearchR01AI116794 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H. · 2016 to 2020
$2.9M
Bioinformatics Strategies for Multidimensional Brain Imaging GeneticsR01LM011360 · NLM · INDIANA UNIVERSITY INDIANAPOLIS · PI MOORE, JASON H., SAYKIN, ANDREW J · 2012 to 2015
$1.4M
Bioinformatics Approaches to Visual Disease GeneticsR01EY022300 · NEI · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H. · 2012 to 2014
$947k
NCATS NIH HHS U01 TR001263NEI NIH HHS R01 EY022300NHLBI NIH HHS R01 HL134015NIAID NIH HHS R01 AI116794NIDDK NIH HHS U01 DK112217NIDDK NIH HHS UC4 DK112217NIEHS NIH HHS P30 ES013508NLM NIH HHS R01 LM009012NLM NIH HHS R01 LM010098NLM NIH HHS R01 LM011360
6 · The paper itself

Abstract

Feature selection plays a critical role in biomedical data mining, driven by increasing feature dimensionality in target problems and growing interest in advanced but computationally expensive methodologies able to model complex associations. Specifically, there is a need for feature selection methods that are computationally efficient, yet sensitive to complex patterns of association, e.g. interactions, so that informative features are not mistakenly eliminated prior to downstream modeling. This paper focuses on Relief-based algorithms (RBAs), a unique family of filter-style feature selection algorithms that have gained appeal by striking an effective balance between these objectives while flexibly adapting to various data characteristics, e.g. classification vs. regression. First, this work broadly examines types of feature selection and defines RBAs within that context. Next, we introduce the original Relief algorithm and associated concepts, emphasizing the intuition behind how it works, how feature weights generated by the algorithm can be interpreted, and why it is sensitive to feature interactions without evaluating combinations of features. Lastly, we include an expansive review of RBA methodological research beyond Relief and its popular descendant, ReliefF. In particular, we characterize branches of RBA research, and provide comparative summaries of RBA algorithms including contributions, strategies, functionality, time complexity, adaptation to key data characteristics, and software availability.

Indexed as

AlgorithmsComputational BiologyData MiningHumansModels, StatisticalRegression AnalysisSoftwareEpistasisFeature interactionFeature selectionFeature weightingFilterReliefF

Identifiers

PMID30031057
PMCPMC6299836

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.