Evidence map›Paper›PMID 30030912›Full record

ReviewESC heart failure2018

Pulmonary hypertension in chronic heart failure: definitions, advances, and unanswered issues.

Emmanuelle Berthelot, Fabrice Bauer, Jean-Christophe Eicher, Erwan Flécher, Barnabas Gellen, Julien Guihaire, Damien Guijarro, Gérald Roul, Muriel Salvat, Christophe Tribouilloy and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in ESC heart failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Emmanuelle BerthelotUniversity of Paris Sud, Le Kremlin-Bicêtre, France.ORCID 0000-0002-0418-3110
Fabrice BauerDepartment of Cardiology, Inserm U1096, Rouen University Hospital, 76031, Rouen, France.
Jean-Christophe EicherDepartment of Cardiology, Dijon University Hospital, 14 rue Paul Gaffarel, 21000, Dijon, France.
Erwan FlécherDepartment of Thoracic and Cardiovascular Surgery, Rennes University Hospital, Rennes, France.
Barnabas GellenELSAN, Polyclinique de Poitiers, 1 rue de la Providence, 86035, Poitiers Cedex, France.
Julien GuihaireCardiothoracic Surgery, Marie Lannelongue Hospital I, University of Paris Sud, 133 avenue de la résistance, 92350, Le Plessis Robinson, France.
Damien GuijarroInstitut Cardio-Vasculaire, Groupement Hospitalier Mutualiste de Grenoble, Grenoble, France.
Gérald RoulFaculté de Médecine, Université de Strasbourg, 4 rue Kirschleger, 67085, Strasbourg Cedex, France.
Muriel SalvatPôle thorax et vaisseaux, CHU Grenoble Alpes, La Tronche, France.
Christophe TribouilloyDepartment of Cardiology, Amiens University Hospital, Amiens, France.
Florian ZoresGroupe Médical Spécialisé, Strasbourg, France.
Nicolas LamblinUniversity of Lille, Service de CHU Lille, Institut Pasteur de Lille, Inserm U1167, F-59000, Lille, France.
Pascal de GrooteCHU Lille, Service de Cardiologie, F-59000, Lille, France.
Thibaud DamyHenry Mondor Hospital, Department of Cardiology, Heart Failure and Amyloidosis Unit, Inserm/UPEC: U955, GRC Amyloid Research Institute, 51 Avenue Maréchal de Lattre de Tassigny, 94000, Créteil, France.
Inserm · FRUniversité de Strasbourg · FRUniversité Paris-Sud · FRCentre Hospitalier Universitaire de Grenoble · FRGroupe Hospitalier Mutualiste de Grenoble · FRMaison des Sciences sociales et des Humanités de Dijon · FRUniversité de Poitiers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension (PH) is a common and severe complication of heart failure (HF). Consequently, HF is the leading cause of PH. For many years, specialists have attempted to better understand the pathophysiology of PH in HF, to define its prevalence and its impact on prognosis in order to improve the therapeutic management of these patients. Nowadays, despite the recent guidelines published on the subject, several points remain unclear or debated, and until now, no study has demonstrated the efficacy of any treatment. The aim of this review is to report the evolution of the concepts on post-capillary PH (diagnosis, prevalence, prognosis, and therapeutics). The main issues are raised, focusing especially on the link between structural alterations and haemodynamic abnormalities, to discuss the possible reasons for treatment failures and future potential targets.

Indexed as

Heart FailureHypertension, PulmonaryGlobal HealthHemodynamicsHumansPrevalencePrognosisClassificationDiagnosisHeart failureHeart transplantationPathophysiologyPulmonary hypertensionTreatment

Identifiers

PMID30030912
PMCPMC6165943
OpenAlexW2883031556

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.