Evidence map›Paper›PMID 30030816›Full record

ReviewPharmacoEconomics2018

Model Structuring for Economic Evaluations of New Health Technologies.

Hossein Haji Ali Afzali, Laura Bojke, Jonathan Karnon

Abstract readReview
PubMed Publisher
In one paragraph

Review in PharmacoEconomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Model parameters influencing the cost-effectiveness of sacubitril/valsartan in heart failure: evidence from a systematic literature review.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hossein Haji Ali AfzaliHealth Economics and Policy Unit, School of Public Health, The University of Adelaide, Level 9, Adelaide Health and Medical Sciences Building, Corner of North Terrace and George Street, Adelaide, SA, 5005, Australia. hossein.hajialiafzali@adelaide.edu.au.
Laura BojkeCentre for Health Economics, University of York, Heslington, York, Y010 5DD, UK.
Jonathan KarnonHealth Economics and Policy Unit, School of Public Health, The University of Adelaide, Level 9, Adelaide Health and Medical Sciences Building, Corner of North Terrace and George Street, Adelaide, SA, 5005, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In countries such as Australia, the UK and Canada, decisions on whether to fund new health technologies are commonly informed by decision analytic models. While the impact of making inappropriate structural choices/assumptions on model predictions is well noted, there is a lack of clarity about the definition of key structural aspects, the process of developing model structure (including the development of conceptual models) and uncertainty associated with the structuring process (structural uncertainty) in guidelines developed by national funding bodies. This forms the focus of this article. Building on the reports of good modelling practice, and recognising the fundamental role of model structuring within the model development process, we specified key structural choices and provided ideas about model structuring for the future direction. This will help to further standardise guidelines developed by national funding bodies, with potential impact on transparency, comprehensiveness and consistency of model structuring. We argue that the process of model structuring and structural sensitivity analysis should be documented in a more systematic and transparent way in submissions to national funding bodies. Within the decision-making process, the development of conceptual models and presentation of all key structural choices would mean that national funding bodies could be more confident of maximising value for money when making public funding decisions.

Indexed as

Models, EconomicBiomedical TechnologyCost-Benefit AnalysisDecision MakingDecision Support TechniquesGuidelines as TopicHumansModels, TheoreticalTechnology Assessment, BiomedicalUncertainty

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.