Evidence map›Paper›PMID 30030749›Full record

ArticleNeuroscience bulletin2018

Spatial Properties of Mismatch Negativity in Patients with Disorders of Consciousness.

Xiaoyu Wang, Rao Fu, Xiaoyu Xia, Xueling Chen, Han Wu, Nicole Landi, Ken Pugh, Jianghong He, Fengyu Cong

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Xiaoyu WangSchool of Biomedical Engineering, Faculty of Electronic Information and Electrical Engineering, Dalian University of Technology, Dalian, 116024, China.ORCID http://orcid.org/0000-0002-0828-6328
Rao FuSchool of Biomedical Engineering, Faculty of Electronic Information and Electrical Engineering, Dalian University of Technology, Dalian, 116024, China.
Xiaoyu XiaDepartment of Neurosurgery, People's Liberation Army General Hospital, Beijing, 100700, China.ORCID http://orcid.org/0000-0003-1349-2940
Xueling ChenDepartment of Neurosurgery, People's Liberation Army General Hospital, Beijing, 100700, China.
Han WuFaculty of Linguistic Science, Beijing Language and Culture University, Beijing, 100083, China.
Nicole LandiHaskins Laboratory, Yale University, New Haven, CT, 06511, USA.
Ken PughHaskins Laboratory, Yale University, New Haven, CT, 06511, USA.
Jianghong HeDepartment of Neurosurgery, People's Liberation Army General Hospital, Beijing, 100700, China. he_jianghong@sina.cn.ORCID http://orcid.org/0000-0001-9470-9966
Fengyu CongSchool of Biomedical Engineering, Faculty of Electronic Information and Electrical Engineering, Dalian University of Technology, Dalian, 116024, China. cong@dlut.edu.cn.ORCID http://orcid.org/0000-0003-0058-2429
Dalian University of Technology · CNHaskins Laboratories · USBeijing Language and Culture University · CNDalian University · CNPeople's Liberation Army No. 150 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent decades, event-related potentials have been used for the clinical electrophysiological assessment of patients with disorders of consciousness (DOCs). In this paper, an oddball paradigm with two types of frequency-deviant stimulus (standard stimuli were pure tones of 1000 Hz; small deviant stimuli were pure tones of 1050 Hz; large deviant stimuli were pure tones of 1200 Hz) was applied to elicit mismatch negativity (MMN) in 30 patients with DOCs diagnosed using the JFK Coma Recovery Scale-Revised (CRS-R). The results showed that the peak amplitudes of MMN elicited by both large and small deviant stimuli were significantly different from baseline. In terms of the spatial properties of MMN, a significant interaction effect between conditions (small and large deviant stimuli) and electrode nodes was centered at the frontocentral area. Furthermore, correlation coefficients were calculated between MMN amplitudes and CRS-R scores for each electrode among all participants to generate topographic maps. Meanwhile, a significant negative correlation between the MMN amplitudes elicited by large deviant stimuli and the CRS-R scores was also found at the frontocentral area. In consequence, our results combine the above spatial properties of MMN in patients with DOCs, and provide a more precise location (frontocentral area) at which to evaluate the correlation between clinical electrophysiological assessment and the level of consciousness.

Indexed as

ElectroencephalographyEvoked PotentialsAcoustic StimulationAdolescentAdultAgedAuditory PerceptionBrain InjuriesConsciousness DisordersFemaleHumansMaleMiddle AgedNeuropsychological TestsSeverity of Illness IndexWavelet AnalysisDisorder of consciousnessEEGMinimally conscious stateMismatch negativityVegetative state

Identifiers

PMID30030749
PMCPMC6060209
OpenAlexW2883593980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.